Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Psychooncology. 2013 Jul;22(7):1457-65. doi: 10.1002/pon.3171. Epub 2012 Sep 7.
This study aims to investigate the evidence of the efficacy of mindfulness-based stress reduction (MBSR) in improving stress, depression and anxiety in breast cancer patients.
An extensive systematic electronic review (PubMed, Embase, CINAHL, PsyArticles, PsycINFO, Scopus, Ovid, Web of Science and The Cochrane Library) and a hand search were carried out from 15 October 2011 to 30 November 2011 to retrieve relevant articles using 'mindfulness' or 'mindfulness-based stress reduction' and 'breast cancer' as keywords. Information about the baseline characteristics of the participants, interventions and findings on perceived stress, depression and anxiety was extracted from each study.
Nine published studies (two randomised controlled trials, one quasi-experimental case-control study and six one-group, pre-intervention and post-intervention studies) up to November 2011 that fulfilled the inclusion criteria were analysed. The pooled effect size (95% CI) for MBSR on stress was 0.710 (0.511-0.909), on depression was 0.575 (0.429-0.722) and on anxiety was 0.733 (0.450-1.017).
On the basis of these findings, MBSR shows a moderate to large positive effect size on the mental health of breast cancer patients and warrants further systematic investigation because it has a potential to make a significant improvement on mental health for women in this group.
本研究旨在探讨正念减压(MBSR)在改善乳腺癌患者压力、抑郁和焦虑方面的疗效证据。
从 2011 年 10 月 15 日至 11 月 30 日,我们进行了广泛的系统电子检索(PubMed、Embase、CINAHL、PsyArticles、PsycINFO、Scopus、Ovid、Web of Science 和 The Cochrane Library)和手工检索,使用“正念”或“正念减压”和“乳腺癌”作为关键词检索相关文章。从每项研究中提取有关参与者基线特征、干预措施以及对压力、抑郁和焦虑的感知的信息。
截至 2011 年 11 月,共有 9 项符合纳入标准的已发表研究(2 项随机对照试验、1 项准实验病例对照研究和 6 项单组、干预前和干预后研究)进行了分析。MBSR 对压力的合并效应大小(95%CI)为 0.710(0.511-0.909),对抑郁的合并效应大小为 0.575(0.429-0.722),对焦虑的合并效应大小为 0.733(0.450-1.017)。
基于这些发现,MBSR 对乳腺癌患者的心理健康有中等到较大的积极效应,值得进一步系统研究,因为它有可能显著改善这一群体女性的心理健康。