James Cook University, Townsville, Australia.
Townsville University Hospital, Townsville, Australia.
Appl Psychol Health Well Being. 2023 Nov;15(4):1733-1749. doi: 10.1111/aphw.12441. Epub 2023 Feb 28.
The clinically standardised mindfulness-based stress reduction (MBSR) has been utilised as an intervention for improving mental health among diabetes patients The present study aimed to assess the effectiveness of mindfulness-based stress reduction (MBSR) on the mental health, haemoglobin A1c (HbA1C), and mindfulness of diabetes patients. A systematic review and meta-analysis approach was employed to review randomised controlled trials published in the English language between the inception of eight databases to July 2022. Eleven articles from 10 studies, with a combined sample size of 718 participants, were included in the systematic review, and nine studies were included in the meta-analysis. In the meta-analysis, outcomes at post-intervention and follow-up were compared between the MBSR intervention and control groups with an adjustment of the baseline values. The results showed that MBSR demonstrated effects at post-intervention and follow-up (in a period between one to 12 months with a mean length of 4.3 months) in reducing anxiety and depressive symptoms, and enhancing mindfulness, with large effect sizes. However, the effect of MBSR on reducing stress was observed at follow-up, but not at post-intervention. Effects of MBSR on HbA1C were not detected at post-intervention and follow-up. The findings suggest that MBSR appears to be an effective treatment for improving mental health conditions and mindfulness in people with diabetes. The measurement of cortisol is recommended to be used as a biological measure to evaluate the effectiveness of MBSR in diabetes patients in future research.
基于正念的减压（MBSR）被临床标准化，已被用于改善糖尿病患者的心理健康。本研究旨在评估基于正念的减压（MBSR）对糖尿病患者心理健康、糖化血红蛋白（HbA1c）和正念的影响。采用系统评价和荟萃分析方法，对 2022 年 7 月之前在英语数据库中发表的随机对照试验进行综述。系统综述纳入了 10 项研究中的 11 篇文章，共有 718 名参与者，9 项研究纳入荟萃分析。荟萃分析中，将干预组和对照组的基线值进行调整，比较干预后和随访时的结果。结果显示，MBSR 在干预后和随访时（1 至 12 个月，平均 4.3 个月）均能有效减轻焦虑和抑郁症状，提高正念水平，效果显著。然而，MBSR 对降低压力的效果仅在随访时观察到，而在干预后未观察到。MBSR 对 HbA1c 的影响在干预后和随访时均未检测到。研究结果表明，MBSR 似乎是一种有效的治疗方法，可改善糖尿病患者的心理健康状况和正念水平。建议在未来的研究中，使用皮质醇测量作为生物指标来评估 MBSR 在糖尿病患者中的效果。
