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基于机构的新生儿护理是否能改善新生儿结局?证据综述。

Does facility based newborn care improve neonatal outcomes? A review of evidence.

机构信息

Indian Institute of Public Health, Delhi, India.

出版信息

Indian Pediatr. 2012 Aug;49(8):651-8. doi: 10.1007/s13312-012-0135-0.

Abstract

CONTEXT

Facility based newborn care is gaining importance as an intervention aiming at reduction of neonatal mortality.

OBJECTIVE

To assess different factors that affect effectiveness of facility based newborn care on neonatal outcomes.

EVIDENCE ACQUISITION

Electronic search using key search engines along with search of grey literature manually. Observational and interventional studies published between 1966-Aug 2010 in English having a change in neonatal mortality as an outcome measure were considered.

RESULTS

A total of 40 articles were fully reviewed for generating synthesized evidence. All were observational studies. The exposure variables that affected neonatal outcomes were grouped into three categories- regionalization of perinatal care (17 articles), strengthening of lower level neonatal facilities (12), and other miscellaneous factors (11). Regionalization played a key role in advancing newborn care practices. It increased in-utero transfer of high risk newborns and improved survival outcomes especially for very low birth weight neonates at level III facilities. It led to reduction in neonatal mortality owing primarily to enhanced survival of low birth weight infants. Strengthening of lower level units contributed significantly in reducing neonatal mortality. High patient volume (>2,000 deliveries/year), inborn status, availability of referral system and inter-facility transfers, and adequate nursing care staff in neonatal units also demonstrated protective effect in averting neonatal deaths.

CONCLUSIONS

Countries investing in facility based newborn care should give impetus to establishing regionalized systems of perinatal care. Strengthening of lower level units with high case loads, can yield optimal reduction in NMR.

摘要

背景

以降低新生儿死亡率为目标的医疗机构为基础的新生儿护理日益受到重视。

目的

评估影响医疗机构为基础的新生儿护理对新生儿结局的有效性的不同因素。

证据获取

使用主要搜索引擎进行电子检索,并手动搜索灰色文献。考虑了 1966 年 8 月至 2010 年期间发表的以新生儿死亡率为结局指标的观察性和干预性研究,且研究必须为英文。

结果

共对 40 篇文章进行了全面审查,以生成综合证据。所有研究均为观察性研究。影响新生儿结局的暴露变量分为三类:围产期护理的区域化(17 篇文章)、加强基层新生儿设施(12 篇)和其他杂项因素(11 篇)。区域化在推进新生儿护理实践中发挥了关键作用。它增加了高危新生儿的宫内转移,并改善了生存结局,特别是在三级设施中极低出生体重儿的生存结局。它导致新生儿死亡率的降低,主要是由于低出生体重儿的存活率提高。加强基层单位也为降低新生儿死亡率做出了重大贡献。高患者量(>2000 例/年)、出生状态、转诊系统和机构间转院的可用性以及新生儿病房有足够的护理人员,也显示出避免新生儿死亡的保护作用。

结论

投资医疗机构为基础的新生儿护理的国家应积极建立围产期护理的区域化系统。加强具有高病例量的基层单位,可以最大限度地降低 NMR。

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