成功治疗伴有少汗症的树胶样细胞 CD8+蕈样肉芽肿：用伏立诺他和维 A 酸。

Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids.

机构信息

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

出版信息

Australas J Dermatol. 2013 Nov;54(4):e82-4. doi: 10.1111/j.1440-0960.2012.00944.x. Epub 2012 Sep 11.

DOI:10.1111/j.1440-0960.2012.00944.x

Abstract

We describe a 34-year-old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF-affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control.

摘要

我们描述了一名 34 岁的日本男性，患有伴有少汗症的侵袭性 CD8+蕈样肉芽肿（MF），接受了伏立诺他和维 A 酸治疗。有趣的是，真皮抗菌肽的免疫组织化学染色显示小汗腺中的汗液减少，而碘淀粉法汗液试验证明 MF 受累区域存在少汗症。在联合治疗 6 个月后，患者的晚期 MF 得到了控制。