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[增强型射频消融新技术治疗巨大肝血管瘤安全有效]

[The new technology of enhanced radiofrequency ablation is safe and effective for treating giant hepatic hemangioma].

作者信息

Zou Hua, Yan Jun, Wu Yan-xia, Ou Xia, Li Xiao-wu, Xia Feng, Ma Kuan-sheng, Bie Ping

机构信息

Hepatobiliary Surgery Institute of PLA, Southwest Hospital, third Military Medical University, Chongqing 400038, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2012 Apr;20(4):261-5. doi: 10.3760/cma.j.issn.1007-3418.2012.04.007.

Abstract

OBJECTIVE

To determine the safety and efficacy of the enhanced radiofrequency ablation (RFA) new technology for treatment of giant hepatic hemangiomas.

METHODS

From August 2010 to September 2011, 30 patients with giant hepatic hemangiomas (average diameter: 7.7+/-1.9 cm, range: 5.0 to 12.8 cm) were treated with enhanced RFA. The original lesion diameter, enhanced radiofrequency duration, and cases of RFA-induced burning were recorded. Cases requiring a second RFA treatment were also recorded. Correlation analysis was carried out to determine the association of enhanced RFA with adverse events and change in lesion diameter.

RESULTS

The rate of completely destroyed lesions by enhanced RFA was 70.96%, and the total rate of reduced lesions was 87.1%. No severe adverse events occurred. The duration of enhanced radiofrequency correlated positively with the original lesion diameter (r=0.687, P less than 0.01). The enhanced RFA treatment significantly reduced the average lesion diameter (follow-up: 6.2+/-1.8 cm; t=6.417, P less than 0.01).

CONCLUSION

The new minimally-invasive technology of enhanced radiofrequency ablation is effective and safe for treating giant hepatic hemangiomas and produces an obvious, short-term curative effect.

摘要

目的

确定增强型射频消融(RFA)新技术治疗巨大肝血管瘤的安全性和有效性。

方法

2010年8月至2011年9月,30例巨大肝血管瘤患者(平均直径:7.7±1.9 cm,范围:5.0至12.8 cm)接受增强型RFA治疗。记录原发病灶直径、增强射频持续时间以及RFA引起灼烧的病例。还记录需要进行第二次RFA治疗的病例。进行相关性分析以确定增强型RFA与不良事件及病灶直径变化之间的关联。

结果

增强型RFA使病灶完全毁损率为70.96%,病灶缩小总率为87.1%。未发生严重不良事件。增强射频持续时间与原发病灶直径呈正相关(r = 0.687,P < 0.01)。增强型RFA治疗显著缩小了平均病灶直径(随访时:6.2±1.8 cm;t = 6.417,P < 0.01)。

结论

增强型射频消融这项新的微创技术治疗巨大肝血管瘤有效且安全,可产生明显的短期疗效。

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