Wang Xing, Meng Jian, Zhang Jie, Wu Ruihan, Gu Jianmin, Shao Cuiling, Han Kun
Department of Stomatology, The Central Hospital of Xuzhou, Xuzhou Clinical School of Xuzhou Medical College, Xuzhou, Jiangsu 221009, P.R. China.
Exp Ther Med. 2016 Dec;12(6):3670-3674. doi: 10.3892/etm.2016.3804. Epub 2016 Oct 13.
The aim of the study was to investigate the clinical effect of radiofrequency (RF) ablation combined with digital subtraction angiography (DSA)-guided anhydrous ethanol injection sclerotherapy in the treatment of high-return flow venous malformation (VM). Forty-one patients who were diagnosed as high-return flow VM with clinical and radiographic evidence were divided into the observation group (n=19) and control group (n=22) by random number table. All the patients received DSA-guided anhydrous ethanol injection sclerotherapy while the patients in the observation group were given RF ablation in addition. The clinical effect, treatment times and adverse effects of the two groups were analyzed. The effectiveness of the observation group was significantly higher than that of the control group (94.7 vs. 81.8%). Facial paralysis occurred in three patients (13.6%) after ethanol injection in the control group, while the observation group had no facial nerve injury after treatment. The patients in the observation group had significantly fewer number of ethanol injections. RF can improve the efficacy of high-return flow VM and reduce the number of ethanol injections. The scheme is safe and effective, which is worth expanding in clinical practice.
本研究旨在探讨射频(RF)消融联合数字减影血管造影(DSA)引导下无水乙醇注射硬化治疗高回流型静脉畸形(VM)的临床效果。将41例经临床及影像学证实诊断为高回流型VM的患者,通过随机数字表法分为观察组(n = 19)和对照组(n = 22)。所有患者均接受DSA引导下无水乙醇注射硬化治疗,观察组患者在此基础上还接受了RF消融治疗。分析两组的临床效果、治疗次数及不良反应。观察组的有效率显著高于对照组(94.7%对81.8%)。对照组有3例患者(13.6%)在乙醇注射后出现面瘫,而观察组治疗后无面神经损伤。观察组患者的乙醇注射次数明显较少。RF可提高高回流型VM的疗效并减少乙醇注射次数。该方案安全有效,值得在临床实践中推广。