Bordeaux University 2 and University Medical Center of Bordeaux, Bordeaux, France.
J Thorac Cardiovasc Surg. 2013 Aug;146(2):302-5. doi: 10.1016/j.jtcvs.2012.07.026. Epub 2012 Sep 7.
Management of pacemaker infection in pacing-dependent patients is often challenging. Typically, temporary pacing is used while antibiotic therapy is given for a number of days before reimplantation of a new endocardial system. This results in a prolonged hospital stay and complications associated with temporary pacing. In this study, we examine the feasibility of performing a single combined procedure of epicardial pacemaker implantation followed by system extraction.
One hundred consecutive infected pacemaker-dependent patients underwent implantation of 2 epicardial ventricular leads and were converted to a ventricular demand pacing system. The infected pacing system was then extracted during the same procedure. Patients were followed up for 12 months.
Significant pericardial bleeding developed during the procedure in 3 patients. The presence of the pericardial drain positioned during the implantation of the epicardial pacing system meant that cardiac tamponade did not occur, allowing surgical repair with sternotomy to be carried out under stable hemodynamic conditions. Two of these 100 patients died in the 30-day postoperative period; 1 death was due to septic shock and 1 to pulmonary distress. Median 1-year epicardial pacing thresholds were stable and excellent (1.4 ± 0.9 volts). However, 1 of the 2 leads developed increased thresholds in 6 patients, which led to the exclusive use of other ventricular lead.
A single combined procedure of surgical epicardial pacemaker implantation and pacemaker system extraction appears to be a safe and effective method for managing pacemaker-dependent patients with infected pacemakers.
起搏依赖患者的起搏器感染管理常常具有挑战性。通常,在新的心内膜系统重新植入之前,会使用临时起搏,同时给予抗生素治疗数天。这会导致住院时间延长,并出现与临时起搏相关的并发症。在这项研究中,我们研究了行单次联合心外膜起搏器植入术和系统取出术的可行性。
100 例感染性起搏器依赖患者接受了 2 个心外膜心室导联的植入,并转换为心室按需起搏系统。随后在同一手术中取出感染的起搏系统。患者随访 12 个月。
3 例患者在手术过程中出现明显的心包积血。心包引流管在心外膜起搏系统植入过程中的存在意味着没有发生心脏压塞,允许在稳定的血流动力学条件下进行经胸骨切开术的外科修复。这 100 例患者中有 2 例在术后 30 天内死亡;1 例死于感染性休克,1 例死于呼吸窘迫。中位 1 年的心外膜起搏阈值稳定且良好(1.4±0.9 伏)。然而,在 6 例患者中,其中 2 个导联中的 1 个导联出现了阈值增加的情况,导致仅使用其他心室导联。
单次联合心外膜起搏器植入术和起搏器系统取出术似乎是一种安全有效的方法,可用于管理感染性起搏器的起搏依赖患者。