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一名88岁女性十二指肠肿瘤表现为获得性血友病：一例临床病例及文献复习

Duodenal tumor presenting as acquired hemophilia in an 88-year-old woman: a clinical case and review of the literature.

作者信息

Murray Nigel P, Moncada Juan Carlos, Moran Marcelo

机构信息

Facultad de Medicina, Universidad Mayor, Renato Sánchez 4369, Las Condes, Santiago 27550224, Chile.

出版信息

Case Rep Gastrointest Med. 2012;2012:203801. doi: 10.1155/2012/203801. Epub 2012 Aug 26.

DOI:10.1155/2012/203801
PMID:22966469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3432527/
Abstract

Acquired hemophilia is a rare disease, presenting with severe hemorrhage, we present a case caused by a duodenal tumor, the clinical management, ethical implications, treatment recommendations, and a review of the literature.

摘要

获得性血友病是一种罕见疾病，表现为严重出血，我们报告一例由十二指肠肿瘤引起的病例，包括临床管理、伦理问题、治疗建议及文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/3432527/7808f9e44ca3/CRIM.GM2012-203801.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/3432527/f8727c54a864/CRIM.GM2012-203801.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/3432527/7808f9e44ca3/CRIM.GM2012-203801.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/3432527/f8727c54a864/CRIM.GM2012-203801.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/3432527/7808f9e44ca3/CRIM.GM2012-203801.002.jpg

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本文引用的文献

1
[Acquired hemophilia as the presenting manifestation of neoplasia: diagnostic workup and monitoring].[获得性血友病作为肿瘤的首发表现：诊断检查与监测]
Rev Med Interne. 2009 Jul;30(7):630-3. doi: 10.1016/j.revmed.2008.09.001. Epub 2008 Oct 23.
2
The diagnosis and management of factor VIII and IX inhibitors: a guideline from the United Kingdom Haemophilia Centre Doctors Organisation.凝血因子VIII和IX抑制物的诊断与管理：英国血友病中心医生组织指南
Br J Haematol. 2006 Jun;133(6):591-605. doi: 10.1111/j.1365-2141.2006.06087.x.
3
Acquired hemophilia A: a concise review.
获得性血友病A：简要综述。
Am J Hematol. 2005 Sep;80(1):55-63. doi: 10.1002/ajh.20390.
4
Treatment of patients with acquired inhibitors.获得性抑制剂患者的治疗。
J Thromb Haemost. 2005 Mar;3(3):595-7. doi: 10.1111/j.1538-7836.2005.01149.x.
5
Rituximab for autoimmune haemophilia: a proposed treatment algorithm.
Haemophilia. 2005 Jan;11(1):13-9. doi: 10.1111/j.1365-2516.2005.01060.x.
6
Rare acquired bleeding disorders.罕见的获得性出血性疾病。
Rev Clin Exp Hematol. 2001 Dec;5(4):405-29; quiz following 431. doi: 10.1046/j.1468-0734.2001.00050.x.
7
Acquired hemophilia.获得性血友病
Rev Clin Exp Hematol. 2001 Dec;5(4):389-404; quiz following 431. doi: 10.1046/j.1468-0734.2001.00049.x.
8
Inhibitors against factor VIII in patients with cancer. Analysis of 41 patients.癌症患者中针对凝血因子VIII的抑制剂。41例患者的分析。
Cancer. 2001 Mar 15;91(6):1067-74. doi: 10.1002/1097-0142(20010315)91:6<1067::aid-cncr1101>3.0.co;2-4.
9
Acquired haemophilia.获得性血友病。
Baillieres Clin Haematol. 1998 Jun;11(2):287-303. doi: 10.1016/s0950-3536(98)80049-8.
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Acquired hemophilia due to factor VIII inhibitors in 34 patients.34例因VIII因子抑制物导致的获得性血友病
Am J Med. 1998 Nov;105(5):400-8. doi: 10.1016/s0002-9343(98)00289-7.