Section of Stroke and Neurocritical Care, Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, 60612, USA.
Curr Cardiol Rep. 2012 Dec;14(6):732-40. doi: 10.1007/s11886-012-0304-8.
Cardiovascular disease and dementia are common in the elderly and are major causes of disability in the general population. The public health burden of dementia is projected to increase as life expectancy increases in the United States and elsewhere. Epidemiological studies suggest that these once believed unrelated conditions, heart disease and dementia, may be linked by shared common risks and pathogenic elements. These observations have sparked the notion that prevention or modification of certain vascular risk factors and proper management of cardiovascular disease may prevent the development or progression of dementia including Alzheimer's disease. In this article, the authors discuss the association between cognitive impairment and atrial fibrillation, coronary artery disease, congestive heart failure, and cardiovascular procedures.
心血管疾病和痴呆在老年人中很常见,也是普通人群残疾的主要原因。随着美国和其他国家预期寿命的增加,痴呆的公共卫生负担预计将会增加。流行病学研究表明,这些曾经被认为不相关的疾病,心脏病和痴呆,可能通过共同的风险因素和发病因素联系在一起。这些观察结果引发了这样一种观点,即预防或改变某些血管危险因素和适当管理心血管疾病可能预防痴呆包括阿尔茨海默病的发生或进展。在本文中,作者讨论了认知障碍与心房颤动、冠状动脉疾病、充血性心力衰竭和心血管手术之间的关联。