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心肌炎的神经系统表现。

Neurological Manifestations of Myocarditis.

机构信息

Department of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, 912 S. Wood Street, M/C 796, Chicago, IL, 172C60612, USA.

出版信息

Curr Neurol Neurosci Rep. 2022 Jul;22(7):363-374. doi: 10.1007/s11910-022-01203-9. Epub 2022 May 19.

Abstract

PURPOSE OF REVIEW

The present review discusses the neurological complications associated with myocarditis of different etiologies.

RECENT FINDINGS

Myocarditis can be idiopathic or caused by different conditions, including toxins, infections, or inflammatory diseases. Clinical findings are variable and range from mild self-limited shortness of breath or chest pain to hemodynamic instability which may result in cardiogenic shock and death. Several neurologic manifestations can be seen in association with myocarditis. Tissue remodeling, fibrosis, and myocyte dysfunction can result in heart failure and arrhythmias leading to intracardiac thrombus formation and cardioembolism. In addition, peripheral neuropathies, status epilepticus, or myasthenia gravis have been reported in association with specific types of myocarditis. Multiple studies suggest the increasing risk of neurologic complications in patients with myocarditis. Neurologists should maintain a high suspicion of myocarditis in cases presenting with both cardiovascular and neurological dysfunction without a clear etiology.

摘要

目的综述

本文讨论了不同病因引起的心肌炎相关的神经系统并发症。

最近的发现

心肌炎可为特发性或由不同病因引起,包括毒素、感染或炎症性疾病。临床表现多种多样,从轻至中度的自限性呼吸急促或胸痛,到血流动力学不稳定,可导致心源性休克和死亡。心肌炎可伴有多种神经系统表现。组织重构、纤维化和心肌细胞功能障碍可导致心力衰竭和心律失常,从而导致心内血栓形成和心源性栓塞。此外,还报道了与特定类型心肌炎相关的周围神经病、癫痫持续状态或重症肌无力。多项研究表明,心肌炎患者发生神经系统并发症的风险增加。当出现心血管和神经系统功能障碍而无明确病因时,神经科医生应高度怀疑心肌炎。

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