Chen C R, Huang Z D, Lo Z X, Cheng T O
Department of Cardiology, Guangdong Provincial Cardiovascular Institute, China.
Am Heart J. 1990 Jan;119(1):102-11. doi: 10.1016/s0002-8703(05)80089-4.
To compare the single rubber-nylon balloon and double polyethylene balloon techniques, 94 patients with rheumatic mitral stenosis underwent percutaneous transseptal balloon mitral valvuloplasty between November 1985 and September 1988. The single balloon technique was used in 73 patients and the double balloon technique was used in 21. The two groups were similar in age, weight, severity of the lesion, and cardiac functional status. The mean mitral valve diastolic gradient decreased from 17.9 +/- 6.5 to 2.9 +/- 3.1 mm Hg (p less than 0.001), 18.5 +/- 6.7 to 5.8 +/- 3.1 mm Hg (p less than 0.001), and 18.1 +/- 5.9 to 3.2 +/- 3.7 mm Hg (p less than 0.001) in the single balloon group, double balloon group, and the entire series, respectively. The final mitral diastolic gradient in the single balloon group was lower than in the double balloon group (p less than 0.05). Complications in the single balloon group were lower than in the double balloon group. Additional advantages of single over double balloon technique were easier maneuverability and higher success rate. The initial and long-term follow-up results confirmed the earlier impressions that percutaneous transseptal balloon mitral valvuloplasty is an effective and safe nonsurgical method of treatment for rheumatic mitral stenosis, and the single rubber-nylon balloon technique is at least as effective as, if not superior to, the double polyethylene balloon technique.
为比较单橡胶尼龙球囊技术和双聚乙烯球囊技术，1985年11月至1988年9月期间，94例风湿性二尖瓣狭窄患者接受了经皮经房间隔球囊二尖瓣成形术。73例患者采用单球囊技术，21例采用双球囊技术。两组在年龄、体重、病变严重程度和心功能状态方面相似。单球囊组、双球囊组和整个系列中，二尖瓣舒张期平均压差分别从17.9±6.5降至2.9±3.1mmHg（p＜0.001）、18.5±6.7降至5.8±3.1mmHg（p＜0.001）和18.1±5.9降至3.2±3.7mmHg（p＜0.001）。单球囊组最终的二尖瓣舒张期压差低于双球囊组（p＜0.05）。单球囊组的并发症低于双球囊组。单球囊技术相对于双球囊技术的其他优势在于操作更简便、成功率更高。初始及长期随访结果证实了早期的印象，即经皮经房间隔球囊二尖瓣成形术是治疗风湿性二尖瓣狭窄的一种有效且安全的非手术方法，并且单橡胶尼龙球囊技术即便不优于双聚乙烯球囊技术，至少与之效果相当。
