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猪作为临床颅面研究的实验模型。

The pig as an experimental model for clinical craniofacial research.

机构信息

Institute of Animal Physiology and Genetics, vvi, Academy of Sciences of Czech Republic, Brno, Czech Republic.

出版信息

Lab Anim. 2012 Oct;46(4):269-79. doi: 10.1258/la.2012.012062. Epub 2012 Sep 11.

DOI:10.1258/la.2012.012062
PMID:22969144
Abstract

The pig represents a useful, large experimental model for biomedical research. Recently, it has been used in different areas of biomedical research. The aim of this study was to review the basic anatomical structures of the head region in the pig in relation to their use in current research. Attention was focused on the areas that are frequently affected by pathological processes in humans: the oral cavity with teeth, salivary gland, orbit, nasal cavity and paranasal sinuses, maxilla, mandible and temporomandibular joint. Not all of the structures have an equal morphology in the pig and human, and these morphological dissimilarities must be taken into account before choosing the pig as an experimental model for regenerative medicine.

摘要

猪是一种有用的、大型的实验动物模型,尤其适用于生物医学研究。最近,它已被应用于生物医学研究的不同领域。本研究旨在综述猪头部的基本解剖结构及其在当前研究中的应用。重点关注的是那些在人类中经常受到病理过程影响的区域:口腔及其牙齿、唾液腺、眼眶、鼻腔和鼻旁窦、上颌骨、下颌骨和颞下颌关节。并非猪和人类的所有结构都具有相同的形态,因此在选择猪作为再生医学的实验模型之前,必须考虑这些形态差异。

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