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一种猪模型:颌面外科眼眶的手术解剖学

A porcine model: surgical anatomy of the orbit for maxillofacial surgery.

作者信息

Kyllar Michal, Štembírek Jan, Danek Zdenek, Hodan Radek, Stránský Jiří, Machoň Vladimír, Foltán René

机构信息

Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic Companion Care Animal Surgery, Broadstairs, Kent, UK.

Institute of Animal Physiology and Genetics, V.v.i., Academy of Sciences of Czech Republic, Brno, Czech Republic Department of Oral and Maxillofacial Surgery, University Hospital, Ostrava, Ostrava-Poruba, Czech Republic

出版信息

Lab Anim. 2016 Apr;50(2):125-36. doi: 10.1177/0023677215577923. Epub 2015 Apr 29.

Abstract

Due to its similarity to humans, the pig has proven to be a suitable biomodel for both research purposes and for training medical professionals, particularly in surgical specializations. For example, new implant materials have been tested on pig jaws and pigs have also been used in the development of new surgical techniques. For optimizing the effectiveness of such research or training, detailed data on the anatomy of their particular features are needed. At present, however, only limited information related to surgical and imaging anatomy of the facial and orbital areas of the pig and its comparison to human structures from the experimental surgery point of view is available in the literature. The aim of this study was to obtain such data and to compare the morphological structures of the porcine and human orbital regions and to lay down the foundation for practical use in experimental surgery. Ten pig heads were examined using computed tomography (CT) and magnetic resonance imaging (MRI) and, subsequently, a dissection of the orbit was carried out. Attention was focused on the structure of the orbit (floor, rim and nerves) frequently affected by pathological processes in humans (such as trauma, infection or tumours) and which consequently are frequently the subject of maxillofacial surgery. The porcine orbit is suitable for use in experimental medicine. However, if used in experiments, its anatomical peculiarities must be taken into consideration. Our study presents a foundation of basic knowledge for researchers who plan to use the pig as a biomedical model to investigate alternative treatments in the head region.

摘要

由于猪与人类的相似性,它已被证明是一种适合用于研究目的和培训医学专业人员的生物模型,尤其是在外科专业领域。例如,新型植入材料已在猪颌骨上进行测试,猪也被用于新手术技术的开发。为了优化此类研究或培训的效果,需要有关其特定特征解剖结构的详细数据。然而,目前从实验手术的角度来看,关于猪面部和眼眶区域的外科及影像解剖学以及与人类结构比较的文献资料有限。本研究的目的是获取此类数据,比较猪和人类眼眶区域的形态结构,并为实验手术的实际应用奠定基础。使用计算机断层扫描(CT)和磁共振成像(MRI)对10个猪头进行了检查,随后对眼眶进行了解剖。重点关注眼眶结构(眶底、眶缘和神经),这些结构在人类中经常受到病理过程(如创伤、感染或肿瘤)的影响,因此经常是颌面外科手术的对象。猪眼眶适用于实验医学。然而,如果用于实验,必须考虑其解剖学特点。我们的研究为计划将猪用作生物医学模型来研究头部区域替代治疗方法的研究人员提供了基础知识。

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