Cardoso Luciana S, Costa Daniela M, Almeida Maria Cecília F, Souza Robson P, Carvalho Edgar M, Araujo Maria Ilma, Oliveira Ricardo R
Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, 40110-160 Salvador, BA, Brazil.
J Parasitol Res. 2012;2012:796820. doi: 10.1155/2012/796820. Epub 2012 Aug 23.
Protective factors associated with atopy or asthma in rural areas include socioeconomic level, overcrowding, and helminth infection. However, little epidemiological information was originated from schistosomiasis areas. This study aimed to investigate factors associated with asthma in a schistosomiasis endemic area. A questionnaire was used to obtain information on demographics, socioeconomic, and environmental features. The ISAAC questionnaire was used to identify individuals with asthma. Parasitological exam was done in all participants and skin prick test to aeroallergens in all asthmatics. Prevalence of Schistosoma mansoni infection was 57.4% and Ascaris lumbricoides, 30.8%. Asthma was found in 13.1% of the population, and 35.1% of them had a positive SPT. Active and passive smoking was positively associated with asthma, whereas A. lumbricoides was negatively associated. In a schistosomiasis hyperendemic region, current infection with A. lumbricoides is protective against asthma. However, we cannot rule out the involvement of S. mansoni infection in this process.
农村地区与特应性或哮喘相关的保护因素包括社会经济水平、居住拥挤程度和蠕虫感染。然而，血吸虫病流行地区的流行病学信息较少。本研究旨在调查血吸虫病流行地区与哮喘相关的因素。采用问卷调查获取人口统计学、社会经济和环境特征方面的信息。使用国际儿童哮喘及过敏研究（ISAAC）问卷来识别哮喘患者。对所有参与者进行寄生虫学检查，并对所有哮喘患者进行吸入性变应原皮肤点刺试验。曼氏血吸虫感染率为57.4%，蛔虫感染率为30.8%。在13.1%的人群中发现了哮喘，其中35.1%的人皮肤点刺试验呈阳性。主动和被动吸烟与哮喘呈正相关，而蛔虫感染与哮喘呈负相关。在血吸虫病高度流行地区，当前蛔虫感染对哮喘具有保护作用。然而，我们不能排除曼氏血吸虫感染在此过程中的作用。
