Department of Conservative Dentistry and Periodontology, Ludwig-Maximilians-University of Munich, Munich, Germany Helmholtz Zentrum of Munich, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany Institute of Medical Data Management, Biometrics and Epidemiology, Ludwig-Maximilians-University of Munich, Munich, Germany Department of Paediatrics, Technical University of Munich, Munich, Germany Department of Preventive and Paediatric Dentistry, Friedrich-Schiller-University of Jena, Jena, Germany Department of Paediatrics, Marien-Hospital Wesel, Wesel, Germany Dr. von Haunersches Kinderspital, Ludwig-Maximilians-University of Munich, Munich, Germany Bioscience Research Center, College of Dentistry, University of Tennessee, Memphis, TN, USA.
J Public Health Dent. 2014 Winter;74(1):42-9. doi: 10.1111/j.1752-7325.2012.00365.x. Epub 2012 Sep 13.
This epidemiological study aimed to assess the proportion and extent of manifestation of enamel hypomineralization, including molar-incisor-hypomineralization (MIH), in the permanent and primary dentition.
A total of 693 children enrolled in an ongoing birth cohort study (GINIplus-10) were examined at their 10-year follow-up. Enamel hypomineralization was scored in the primary and permanent dentition on a tooth- and surface-related level based on the criteria of the European Academy of Paediatric Dentistry (EAPD). Children were grouped according to their distribution pattern of enamel hypomineralization: children with a minimum of one hypomineralized tooth in the primary dentition (ht ≥ 1) and permanent dentition (HT ≥ 1); with a minimum of one hypomineralization on at least one first permanent molar (MIH); and with hypomineralization on at least one first permanent molar and permanent incisor (M + IH). For each group, the mean values of hypomineralized primary teeth (ht), permanent teeth (HT), and permanent surfaces (HS) were calculated.
The proportion of affected children was 36.5 percent (HT ≥ 1), 14.7 percent (MIH), and 9.4 percent (M + IH); 6.9 percent of the subjects had a minimum of one affected primary tooth (ht ≥ 1). The mean number of hypomineralized permanent teeth and surfaces were 2.3HT/2.9HS (HT ≥ 1), 3.4HT/4.8HS (MIH), and 4.2HT/5.9HS (M + IH). The mean number of hypomineralized primary teeth amounted to 0.1ht in the entire study population.
Enamel hypomineralization can be detected frequently in this study sample. Children with M + IH showed the highest number of affected teeth and surfaces followed by those with MIH.
本流行病学研究旨在评估釉质矿化不全（包括磨牙-切牙矿化不全[MIH]）在恒牙和乳牙中的表现比例和程度。
在一项正在进行的出生队列研究（GINIplus-10）中，共有 693 名儿童在 10 岁随访时接受了检查。根据欧洲儿童牙科学会（EAPD）的标准，在牙齿和表面相关的基础上对乳牙和恒牙的釉质矿化不全进行评分。根据釉质矿化不全的分布模式，将儿童分为以下几类：乳牙（ht≥1）和恒牙（HT≥1）中至少有一颗矿化不全的牙齿；至少有一颗第一恒磨牙（MIH）矿化不全；至少有一颗第一恒磨牙和恒切牙（M+IH）矿化不全。对于每个组，计算矿化不全的乳牙（ht）、恒牙（HT）和恒牙面（HS）的平均值。
受影响儿童的比例分别为 36.5%（HT≥1）、14.7%（MIH）和 9.4%（M+IH）；6.9%的受试者至少有一颗矿化不全的乳牙（ht≥1）。矿化不全恒牙和恒牙面的平均数量分别为 2.3HT/2.9HS（HT≥1）、3.4HT/4.8HS（MIH）和 4.2HT/5.9HS（M+IH）。整个研究人群中矿化不全乳牙的平均数量为 0.1ht。
在本研究样本中，可频繁检测到釉质矿化不全。M+IH 组的患牙和患牙面数量最多，其次是 MIH 组。
