Department of Plastic, Aesthetic and Reconstructive Surgery, Ataturk Training & Research Hospital, Izmir, Turkey.
J Cutan Med Surg. 2012 Sep-Oct;16(5):341-3. doi: 10.1177/120347541201600511.
Malignant pilomatrixoma (also known as pilomatrix carcinoma) is a very rare malignant neoplasm derived from the hair matrix. These slow-growing malignancies of the skin are found in the lower dermis and subcutaneous fat layer. They can exhibit local aggressive behavior or distant metastasis. This malignancy can arise as a solitary lesion de novo or through transformation of a pilomatrixoma over a long period. There is no known distinct etiologic factor or predisposing condition for this kind of malignancy.
We present an interesting case of a 65-year-old man with a pilomatrix carcinoma arising on the previously irradiated face due to the malignant neoplasm of the parotid gland. This is the first report of a pilomatrix carcinoma that has developed on a region that has undergone radiotherapy for another malignancy.
恶性毛囊基质瘤（也称为毛囊母细胞瘤）是一种非常罕见的恶性肿瘤，来源于毛基质。这些生长缓慢的皮肤恶性肿瘤位于真皮下部和皮下脂肪层。它们可能表现出局部侵袭性或远处转移。这种恶性肿瘤可以作为一个孤立的病变首次出现，也可以通过毛母细胞瘤的长期转化出现。目前尚不清楚这种恶性肿瘤的明确病因或易患因素。
我们报告了一个有趣的病例，一名 65 岁男性，由于腮腺恶性肿瘤，曾接受过放疗的面部出现毛囊母细胞瘤。这是首例报道的在因另一种恶性肿瘤接受过放疗的区域发生的毛囊母细胞瘤。
