Institute of oncology of Vojvodina, Sremska Kamenica, Serbia.
Radiat Oncol. 2012 Sep 12;7:155. doi: 10.1186/1748-717X-7-155.
Independent external audits play an important role in quality assurance programme in radiation oncology. The audit supported by the IAEA in Serbia was designed to review the whole chain of activities in 3D conformal radiotherapy (3D-CRT) workflow, from patient data acquisition to treatment planning and dose delivery. The audit was based on the IAEA recommendations and focused on dosimetry part of the treatment planning and delivery processes.
The audit was conducted in three radiotherapy departments of Serbia. An anthropomorphic phantom was scanned with a computed tomography unit (CT) and treatment plans for eight different test cases involving various beam configurations suggested by the IAEA were prepared on local treatment planning systems (TPSs). The phantom was irradiated following the treatment plans for these test cases and doses in specific points were measured with an ionization chamber. The differences between the measured and calculated doses were reported.
The measurements were conducted for different photon beam energies and TPS calculation algorithms. The deviation between the measured and calculated values for all test cases made with advanced algorithms were within the agreement criteria, while the larger deviations were observed for simpler algorithms. The number of measurements with results outside the agreement criteria increased with the increase of the beam energy and decreased with TPS calculation algorithm sophistication. Also, a few errors in the basic dosimetry data in TPS were detected and corrected.
The audit helped the users to better understand the operational features and limitations of their TPSs and resulted in increased confidence in dose calculation accuracy using TPSs. The audit results indicated the shortcomings of simpler algorithms for the test cases performed and, therefore the transition to more advanced algorithms is highly desirable.
独立的外部审计在放射肿瘤学质量保证计划中发挥着重要作用。由国际原子能机构(IAEA)在塞尔维亚支持的审计旨在审查 3D 适形放疗(3D-CRT)工作流程中的整个活动链,从患者数据采集到治疗计划和剂量输送。该审计基于 IAEA 的建议,并侧重于治疗计划和输送过程的剂量学部分。
审计在塞尔维亚的三个放射治疗部门进行。使用计算机断层扫描(CT)单元对人体模型进行扫描,并在本地治疗计划系统(TPS)上为涉及 IAEA 建议的各种光束配置的八个不同测试用例准备治疗计划。根据这些测试用例的治疗计划对人体模型进行照射,并使用电离室测量特定点的剂量。报告了测量值与计算值之间的差异。
针对不同光子束能量和 TPS 计算算法进行了测量。使用先进算法进行的所有测试用例的测量值与计算值之间的偏差均在协议标准范围内,而较简单的算法则观察到较大的偏差。随着光束能量的增加和 TPS 计算算法复杂性的降低,超出协议标准的测量结果数量增加。此外,还检测并纠正了 TPS 中基本剂量学数据的一些错误。
审计帮助用户更好地了解其 TPS 的操作特点和局限性,并提高了对使用 TPS 计算剂量准确性的信心。审计结果表明,对于执行的测试用例,较简单的算法存在缺点,因此非常需要过渡到更先进的算法。