Department of Radiation Oncology, MGM Cancer Institute (Unit of MGM Healthcare Pvt Ltd.), Chennai, India.
Department of Radiation Oncology, Kasturba Medical College (A Constituent Institution of Manipal Academy of Higher Education), Mangalore, Karnataka, India.
Asian Pac J Cancer Prev. 2022 Dec 1;23(12):4155-4162. doi: 10.31557/APJCP.2022.23.12.4155.
Aim of this study is to evaluate the efficacy of inhomogeneity corrections calculated by radiotherapy treatment planning system (TPS) using various densities of materials.
Gammex Computed tomography electron density inserts (EDI's; 14 no's) were used to generate the CT to ED curve with high speed GE CT scanner by noting down the respective HU values of each rod. Treatment plans were generated in XiO TPS with three inhomogeneous phantoms (comprising combination of water, lung and bone equivalent slabs) with different field sizes and for EDI (8 no's) inserted in slots of acrylic tray and validation was carried out using 2D array detector with 20cm×20cm field size for 200 MU. Point dose and fluence measurements were carried with inhomogeneous phantoms combinations and EDI's (placed on the locally fabricated box filled with water medium).
The mean percentage deviations with standard deviation of calculated point doses against measured ones obtained with 2D array detector at iso-center plane for all three inhomogeneous phantom combinations were found to be -1.13%±0.13%, -3.51%±0.14% and -0.63%±0.27% respectively. On point doses measured under each individual EDI, over all percentage deviation with standard deviation observed is -2.04% ± 1.1%.
The described method can be implemented in any newly established radiotherapy department as a routine quality measure of TPS to verify its efficacy in performing of inhomogeneity calculation.
本研究旨在评估放疗计划系统(TPS)使用不同材料密度计算的不均匀性校正的疗效。
使用伽马克斯计算的 CT 电子密度插入物(EDI)(共 14 个),通过记录每个棒的相应 HU 值,在高速 GE CT 扫描仪上生成 CT 到 ED 曲线。在 XiO TPS 中生成三个不均匀体模(包含水、肺和骨等效板的组合)的治疗计划,具有不同的射野大小,并在丙烯酸托盘的插槽中插入 EDI(8 个),使用 20cm×20cm 射野大小的 2D 阵列探测器进行验证,剂量为 200MU。在不均匀体模组合和 EDI(放置在充满水介质的本地制作的盒子上)上进行点剂量和通量测量。
在所有三个不均匀体模组合的等中心平面上,使用 2D 阵列探测器获得的计算点剂量与实测点剂量的平均百分比偏差及其标准差分别为-1.13%±0.13%、-3.51%±0.14%和-0.63%±0.27%。在每个 EDI 下测量的点剂量上,观察到的总百分比偏差及其标准差为-2.04%±1.1%。
该方法可在任何新成立的放疗部门实施,作为 TPS 疗效的常规质量措施,以验证其在不均匀性计算中的功效。