Bahreyni Toossi Mohammad Taghi, Farhood Bagher, Soleymanifard Shokouhozaman
Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Medical Physics and Medical Engineering Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Rep Pract Oncol Radiother. 2017 Sep-Oct;22(5):420-427. doi: 10.1016/j.rpor.2017.06.001. Epub 2017 Aug 18.
The objective was to quantify dose calculation accuracy of TiGRT TPS for head and neck region in radiotherapy.
In radiotherapy of head and neck cancers, treatment planning is difficult, due to the complex shape of target volumes and also to spare critical and normal structures. These organs are often very near to the target volumes and have low tolerance to radiation. In this regard, dose calculation accuracy of treatment planning system (TPS) must be high enough.
Thermoluminescent dosimeter-100 (TLD-100) chips were used within RANDO phantom for dose measurement. TiGRT TPS was also applied for dose calculation. Finally, difference between measured doses () and calculated doses () was obtained to quantify the dose calculation accuracy of the TPS at head and neck region.
For in-field regions, in some points, the TiGRT TPS overestimated the dose compared to the measurements and for other points underestimated the dose. For outside field regions, the TiGRT TPS underestimated the dose compared to the measurements. For most points, the difference values between and for the in-field and outside field regions were less than 5% and 40%, respectively.
Due to the sensitive structures to radiation in the head and neck region, the dose calculation accuracy of TPSs should be sufficient. According to the results of this study, it is concluded that the accuracy of dose calculation of TiGRT TPS is enough for in-field and out of field regions.
本研究旨在量化放疗中头部和颈部区域TiGRT治疗计划系统(TPS)的剂量计算准确性。
在头颈部癌的放疗中,由于靶区形状复杂,且要保护关键和正常组织,治疗计划制定困难。这些器官通常与靶区非常接近,对辐射的耐受性较低。因此,治疗计划系统(TPS)的剂量计算准确性必须足够高。
在RANDO体模内使用热释光剂量仪-100(TLD-100)芯片进行剂量测量。同时应用TiGRT TPS进行剂量计算。最后,通过测量剂量()与计算剂量()之间的差值来量化TPS在头部和颈部区域的剂量计算准确性。
对于射野内区域,在某些点上,TiGRT TPS计算的剂量比测量值高,而在其他点上则比测量值低。对于射野外区域,TiGRT TPS计算的剂量比测量值低。对于大多数点,射野内和射野外区域的与之间的差值分别小于5%和40%。
由于头颈部区域的组织对辐射敏感,TPS的剂量计算准确性应足够高。根据本研究结果,得出TiGRT TPS在射野内和射野外区域的剂量计算准确性足够的结论。