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探讨患者对前列腺癌 PSA 筛查的看法:风险、效果和重要性。

Exploring patient perceptions of PSA screening for prostate cancer: risks, effectiveness, and importance.

机构信息

Hospitalist Group, Kelowna General Hospital, 2268 Pandosy St, Kelowna, BC V1Y 1T2.

出版信息

Can Fam Physician. 2012 Sep;58(9):e502-7.

PMID:22972741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3440291/
Abstract

OBJECTIVE

To study the beliefs of a group of Canadian men regarding the risks, effectiveness, and importance of routine prostate-specific antigen (PSA) testing when used as a screening tool for prostate cancer.

DESIGN

A 1-page questionnaire designed to gauge patient beliefs about PSA screening.

SETTING

Two primary care clinics in Kingston, Ont.

PARTICIPANTS

Seventy-two men aged 41 to 80.

MAIN OUTCOME MEASURES

Whether men believed that the PSA blood test was not risky when used as a screening test for prostate cancer, was effective at preventing death from prostate cancer, and was important for their health.

RESULTS

Fifteen men reported having visited their physicians because of difficulty urinating in the past 2 years, or a personal history of prostate cancer, and were excluded; for these men, the use of the PSA blood test would not be for screening. Of the 57 men considered in the study, 54 (95%) believed that using the PSA blood test as a screening tool for prostate cancer was not risky, 39 (68%) believed that the PSA blood test was good or very good at preventing death from prostate cancer, and 45 (79%) believed that the routine use of the PSA blood test was important or very important for their health. Men in the suggested screening age group of 51 to 70 years (n = 32) had an equally positive impression of PSA screening.

CONCLUSION

Despite a limited body of evidence showing its effectiveness, Canadian men continue to have a favourable impression of PSA screening and remain largely unaware of potential adverse events associated with PSA testing.

摘要

目的

研究一组加拿大男性对前列腺特异性抗原(PSA)检测作为前列腺癌筛查工具的风险、有效性和重要性的看法。

设计

用于评估患者对 PSA 筛查看法的 1 页问卷。

地点

安大略省金斯顿的两家初级保健诊所。

参与者

72 名年龄在 41 至 80 岁的男性。

主要观察指标

男性是否认为 PSA 血液检测作为前列腺癌筛查测试使用时没有风险,是否能有效预防前列腺癌死亡,以及对他们的健康是否重要。

结果

15 名男性报告说在过去 2 年内因排尿困难或个人前列腺癌病史而看过医生,因此被排除在外;对于这些男性来说,PSA 血液检测的使用不是用于筛查。在研究的 57 名男性中,有 54 名(95%)男性认为使用 PSA 血液检测作为前列腺癌筛查工具没有风险,39 名(68%)男性认为 PSA 血液检测在预防前列腺癌死亡方面是好的或非常好的,45 名(79%)男性认为常规使用 PSA 血液检测对他们的健康是重要的或非常重要的。处于建议的筛查年龄组(51 至 70 岁)的男性对 PSA 筛查也有同样积极的印象。

结论

尽管有有限的证据表明 PSA 筛查有效,但加拿大男性对 PSA 筛查仍持有利的看法,并且对与 PSA 检测相关的潜在不良事件仍然知之甚少。

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本文引用的文献

1
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BMJ. 2010 Sep 14;341:c4543. doi: 10.1136/bmj.c4543.
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Prostate-specific antigen tests and prostate cancer screening: an update for primary care physicians.前列腺特异性抗原检测与前列腺癌筛查:基层医疗医生的最新资讯
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Screening and prostate-cancer mortality in a randomized European study.一项欧洲随机研究中的筛查与前列腺癌死亡率
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Mortality results from a randomized prostate-cancer screening trial.一项前列腺癌随机筛查试验的死亡率结果。
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Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement.前列腺癌筛查:美国预防服务工作组建议声明
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Screening for prostate cancer.前列腺癌筛查
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Brief report: physicians and their personal prostate cancer-screening practices with prostate-specific antigen. A national survey.简短报告:医生及其使用前列腺特异性抗原进行前列腺癌筛查的个人做法。一项全国性调查。
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Factors associated with men's use of prostate-specific antigen screening: evidence from Health Information National Trends Survey.与男性使用前列腺特异性抗原筛查相关的因素:来自健康信息国家趋势调查的证据。
Prev Med. 2005 Apr;40(4):461-8. doi: 10.1016/j.ypmed.2004.07.011.
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GP and patient predictors of PSA screening in Australian general practice.澳大利亚全科医疗中前列腺特异性抗原(PSA)筛查的全科医生及患者预测因素
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The benefits of, controversies surrounding, and professional recommendations for routine PSA testing: what do men believe?常规前列腺特异性抗原(PSA)检测的益处、相关争议及专业建议:男性的看法是什么?
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