Department of Otolaryngology, Tokai University, Isehara, Japan.
Head Neck. 2013 Aug;35(8):1162-7. doi: 10.1002/hed.23094. Epub 2012 Sep 13.
The objective of this study was to evaluate the efficacy and safety of minimally invasive transoral en bloc resection of superficial pharyngeal and laryngeal cancers.
Forty-one superficial lesions (from 35 patients) were resected transorally under a surgical microscope using a monopolar cautery. Quality of life (QOL) was assessed using a questionnaire European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35) 1 year after the surgery.
Twenty-eight hypopharyngeal, 5 oropharyngeal, and 8 laryngeal cancers were operated on using this method. The surgical field was widely exposed with a wide-caliber scope or extending laryngoscope. A bimanual procedure under a surgical microscope enabled us to achieve en bloc resection. The local control rate was 98%. No postoperative dyspnea or dysphagia was observed. Postoperative QOL scores were favorable.
Our transoral en bloc resection technique can be easily adopted, and it effectively maintained QOL after treatment.
本研究旨在评估微创经口整块切除表浅性咽和声门癌的疗效和安全性。
在手术显微镜下，使用单极电凝器经口切除 41 个表浅病变（35 例患者）。术后 1 年采用欧洲癌症研究与治疗组织生活质量问卷头颈部模块（EORTC QLQ-H&N35）评估生活质量（QOL）。
采用该方法治疗 28 例下咽癌、5 例口咽癌和 8 例喉癌。手术视野通过大口径内镜或延长喉镜广泛暴露。在手术显微镜下单手操作可实现整块切除。局部控制率为 98%。无术后呼吸困难或吞咽困难。术后 QOL 评分良好。
我们的经口整块切除术技术易于采用，且可有效维持治疗后的 QOL。
