Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford University School of Humanities and Sciences, Stanford, CA 94305, USA.
Sci Transl Med. 2012 Sep 12;4(151):151ps15. doi: 10.1126/scitranslmed.3004631.
Because of a variety of caveats, the safety and effectiveness of interventions in human subjects can only be speculated from animal studies. Careful synthesis of data from multiple animal studies is needed to begin to assess the likelihood of successful cross-species translation (Fay et al., this issue).
由于存在各种注意事项,只能根据动物研究来推测人体干预措施的安全性和有效性。需要仔细综合来自多个动物研究的数据,才能开始评估跨物种成功转化的可能性(Fay 等人,本期)。