Dostović Zikrija, Smajlović Dževdet, Dostović Ernestina, Ibrahimagić Omer Ć
Department of Neurology, University Clinical Centre Tuzla, 75000 Tuzla, Bosnia and Herzegovina.
Cardiovasc Psychiatry Neurol. 2012;2012:429108. doi: 10.1155/2012/429108. Epub 2012 Sep 3.
Objectives. To determine the severity of stroke and mortality in relation to the type of disturbance of consciousness and outcome of patients with disorders of consciousness. Patients and Methods. We retrospectively analyzed 201 patients. Assessment of disorders of consciousness is performed by Glasgow Coma Scale (Teasdale and Jennet, 1974) and the Diagnostic and Statistical Manual of Mental Disorders (Anonymous, 2000). The severity of stroke was determined by National Institutes of Health Stroke Scale (Lyden et al., 2011). Results. Fifty-four patients had disorders of consciousness (26.9%). Patients with disorders of consciousness on admission (P < 0.001) and discharge (P = 0.003) had a more severe stroke than patients without disturbances of consciousness. Mortality was significantly higher in patients with disorders of consciousness (P = 0.0001), and there was no difference in mortality in relation to the type of disturbance of consciousness. There is no statistically significant effect of specific predictors of survival in patients with disorders of consciousness. Conclusion. Patients with disorders of consciousness have a more severe stroke and higher mortality. There is no difference in mortality and severity of stroke between patients with quantitative and qualitative disorders of consciousness. There is no statistically significant effect of specific predictors of survival in patients with disorders of consciousness.
目的。确定与意识障碍类型及意识障碍患者预后相关的中风严重程度和死亡率。患者与方法。我们回顾性分析了201例患者。意识障碍的评估采用格拉斯哥昏迷量表(Teasdale和Jennet,1974年)以及《精神疾病诊断与统计手册》(匿名,2000年)。中风严重程度由美国国立卫生研究院中风量表确定(Lyden等人,2011年)。结果。54例患者存在意识障碍(26.9%)。入院时(P < 0.001)和出院时(P = 0.003)有意识障碍的患者比无意识障碍的患者中风更严重。意识障碍患者的死亡率显著更高(P = 0.0001),且死亡率与意识障碍类型无关。意识障碍患者生存的特定预测因素无统计学显著影响。结论。意识障碍患者中风更严重且死亡率更高。定量和定性意识障碍患者之间的死亡率和中风严重程度无差异。意识障碍患者生存的特定预测因素无统计学显著影响。