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卵巢颗粒细胞瘤破裂作为绝经后女性急腹症的一个病因。

Ruptured granulosa cell tumor of the ovary as a cause of acute abdomen in postmenopausal woman.

作者信息

Oge Tufan, Ozalp S Sinan, Yalcin Omer T, Kabukcuoglu Sare, Arslan Emine

机构信息

Department of Obstetrics and Gynecology, Eskisehir Osmangazi University School of Medicine, 26100 Eskisehir, Turkey.

出版信息

Case Rep Oncol Med. 2012;2012:451631. doi: 10.1155/2012/451631. Epub 2012 Sep 3.

Abstract

Acute abdomen with hemoperitoneum is a very rare entity in postmenopausal women due to gynecologic conditions. A 54-year-old, postmenopausal woman was brought to emergency department with severe abdominal pain. Physical examination revealed acute abdomen findings with 15 cm pelvic mass on the right adnexal region. Immediate exploratory laparotomy was performed. During laparotomy 1000 cc of bloodstained fluid, ruptured and actively bleeding large mass arising from right ovary was observed. Right salpingo-oopherectomy was performed in emergency conditions, and pathology report revealed an adult type of granulosa cell tumor. After this result, staging surgery was performed and patient was diagnosed as granulosa cell tumor stage 1 c. Cisplatin, etoposide, and bleomycin chemotherapy was given. Clinicians should be aware of granulosa cell tumors which may occur at any age and prone to rupture. Frozen section will be helpful in order to avoid incomplete surgeries especially in postmenopausal women presented with intra-abdominal bleeding.

摘要

绝经后女性因妇科疾病出现伴有腹腔积血的急腹症是非常罕见的情况。一名54岁的绝经后女性因严重腹痛被送往急诊科。体格检查发现急腹症表现,右侧附件区有一个15厘米的盆腔肿块。立即进行了剖腹探查术。在剖腹手术中,观察到1000毫升血性液体,右侧卵巢有一个破裂且正在出血的大肿块。在紧急情况下进行了右侧输卵管卵巢切除术,病理报告显示为成人型颗粒细胞瘤。根据这一结果,进行了分期手术,患者被诊断为颗粒细胞瘤1c期。给予了顺铂、依托泊苷和博来霉素化疗。临床医生应意识到颗粒细胞瘤可发生于任何年龄且易于破裂。冰冻切片有助于避免手术不彻底,尤其是对于出现腹腔内出血的绝经后女性。

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