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本文引用的文献

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Successful treatment of adult-type granulosa cell tumor of the ovary by palliative radiotherapy.姑息性放疗成功治疗成人型卵巢颗粒细胞瘤
J Obstet Gynaecol Res. 2012 Feb;38(2):461-5. doi: 10.1111/j.1447-0756.2011.01715.x. Epub 2011 Dec 19.
2
Clinicopathologic characteristics of granulosa cell tumors of the ovary: a multicenter retrospective study.卵巢颗粒细胞瘤的临床病理特征:一项多中心回顾性研究。
J Gynecol Oncol. 2011 Sep;22(3):188-95. doi: 10.3802/jgo.2011.22.3.188. Epub 2011 Sep 28.
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Acute abdomen with hemoperitoneum in a postmenopausal woman.一名绝经后女性出现伴有腹腔积血的急腹症。
J Midlife Health. 2010 Jul;1(2):89-90. doi: 10.4103/0976-7800.76220.
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Abdominal pain in the ED: a 35 year retrospective.急诊科腹痛:35 年回顾性研究。
Am J Emerg Med. 2011 Sep;29(7):711-6. doi: 10.1016/j.ajem.2010.01.045. Epub 2010 May 1.
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Isolated torsion of fallopian tube in a post-menopausal patient: a case report.绝经后患者孤立性输卵管扭转:一例报告
Maturitas. 2007 Jul 20;57(3):325-7. doi: 10.1016/j.maturitas.2007.01.006. Epub 2007 Feb 20.
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Tubo-ovarian abscesses in postmenopausal women: gynecological malignancy until proven otherwise?绝经后女性的输卵管卵巢脓肿:在未被证伪之前是否为妇科恶性肿瘤?
Eur J Obstet Gynecol Reprod Biol. 2004 Jun 15;114(2):203-9. doi: 10.1016/j.ejogrb.2003.10.032.
7
Ruptured ovarian granulosa cell tumors as a cause of the acute abdomen.破裂的卵巢颗粒细胞瘤作为急腹症的一个病因。
Arch Gynecol Obstet. 2003 Jan;267(3):175-6. doi: 10.1007/s00404-001-0269-0.
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Hemoperitoneum in a postmenopausal woman.绝经后女性的腹腔积血。
J Natl Med Assoc. 1998 May;90(5):317-9.
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Evaluation of abdominal pain in the elderly.
Emerg Med Clin North Am. 1996 Aug;14(3):615-27. doi: 10.1016/s0733-8627(05)70270-4.

卵巢颗粒细胞瘤破裂作为绝经后女性急腹症的一个病因。

Ruptured granulosa cell tumor of the ovary as a cause of acute abdomen in postmenopausal woman.

作者信息

Oge Tufan, Ozalp S Sinan, Yalcin Omer T, Kabukcuoglu Sare, Arslan Emine

机构信息

Department of Obstetrics and Gynecology, Eskisehir Osmangazi University School of Medicine, 26100 Eskisehir, Turkey.

出版信息

Case Rep Oncol Med. 2012;2012:451631. doi: 10.1155/2012/451631. Epub 2012 Sep 3.

DOI:10.1155/2012/451631
PMID:22973526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3438719/
Abstract

Acute abdomen with hemoperitoneum is a very rare entity in postmenopausal women due to gynecologic conditions. A 54-year-old, postmenopausal woman was brought to emergency department with severe abdominal pain. Physical examination revealed acute abdomen findings with 15 cm pelvic mass on the right adnexal region. Immediate exploratory laparotomy was performed. During laparotomy 1000 cc of bloodstained fluid, ruptured and actively bleeding large mass arising from right ovary was observed. Right salpingo-oopherectomy was performed in emergency conditions, and pathology report revealed an adult type of granulosa cell tumor. After this result, staging surgery was performed and patient was diagnosed as granulosa cell tumor stage 1 c. Cisplatin, etoposide, and bleomycin chemotherapy was given. Clinicians should be aware of granulosa cell tumors which may occur at any age and prone to rupture. Frozen section will be helpful in order to avoid incomplete surgeries especially in postmenopausal women presented with intra-abdominal bleeding.

摘要

绝经后女性因妇科疾病出现伴有腹腔积血的急腹症是非常罕见的情况。一名54岁的绝经后女性因严重腹痛被送往急诊科。体格检查发现急腹症表现,右侧附件区有一个15厘米的盆腔肿块。立即进行了剖腹探查术。在剖腹手术中,观察到1000毫升血性液体,右侧卵巢有一个破裂且正在出血的大肿块。在紧急情况下进行了右侧输卵管卵巢切除术,病理报告显示为成人型颗粒细胞瘤。根据这一结果,进行了分期手术,患者被诊断为颗粒细胞瘤1c期。给予了顺铂、依托泊苷和博来霉素化疗。临床医生应意识到颗粒细胞瘤可发生于任何年龄且易于破裂。冰冻切片有助于避免手术不彻底,尤其是对于出现腹腔内出血的绝经后女性。