Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, USA.
Prog Mol Biol Transl Sci. 2012;112:417-21. doi: 10.1016/B978-0-12-415813-9.00015-5.
The complexity and interrelationships of human environments are constantly undergoing further definition. The importance of such definition can be realized when such broad environmental categories as natural ecosystems, the agroecosystem, occupational, urban, domestic, and military deployments, all of which can be subdivided into more specialized environments, are considered. Set against this background, it is clear that the principal role of toxicology is risk analysis. Risk analysis consists not only of risk assessment but also risk management and risk communication. New paradigms in hazard assessment are revolutionizing risk assessment, and all aspects, from molecular toxicology to outreach programs, will be involved in future considerations of human environments.
人类环境的复杂性和相互关系在不断得到进一步的定义。当考虑到自然生态系统、农业生态系统、职业、城市、家庭和军事部署等广泛的环境类别,以及所有这些类别都可以进一步细分为更专业的环境时,就可以认识到这种定义的重要性。在这种背景下,很明显,毒理学的主要作用是风险分析。风险分析不仅包括风险评估,还包括风险管理和风险沟通。危害评估的新范例正在彻底改变风险评估,从分子毒理学到外展计划的各个方面都将涉及到人类环境的未来考虑。