Commens C A
Skin and Cancer Foundation, Ashley Centre, Westmead, NSW, Australia.
Br J Dermatol. 1990 Jan;122(1):77-80. doi: 10.1111/j.1365-2133.1990.tb08242.x.
Topical propylene glycol is known to cause elevated serum osmolality in burns patients. Twelve adults with skin disease had quantities of propylene glycol applied to their skin to a maximum of 6.1 g/kg per 24 h for 5 days. Serum electrolyte, lactate and osmolality results remained unchanged during the study. These results suggest that topical propylene glycol may be used in adult dermatological practice without affecting serum osmolality.
