尼泊尔育龄妇女对围孕期叶酸补充的认知：一项横断面研究。

Awareness of periconceptional folic acid supplementation among Nepalese women of childbearing age: a cross-sectional study.

机构信息

Department of General Surgery, Kathmandu Model Hospital, GPO Box: 6064, Pradarshani Marg, Kathmandu, Nepal.

出版信息

Prev Med. 2012 Nov;55(5):511-3. doi: 10.1016/j.ypmed.2012.09.001. Epub 2012 Sep 10.

DOI:10.1016/j.ypmed.2012.09.001

PMID:22975411

Abstract

OBJECTIVE

Maternal folate deficiency is associated with neural tube defects (NTDs), the most common congenital birth defect at Maternity Hospital, Kathmandu, Nepal. NTDs can be prevented with periconceptional folic acid supplementation (FAS). This study was performed to assess the awareness of FAS among women of reproductive age in Kathmandu.

METHODS

A semi-structured questionnaire was administered to 400 randomly selected patients aged 15 to 45 years visiting Kathmandu Model Hospital from May to July 2011, seeking any awareness of FAS, knowledge of its impact on fetal development and knowledge of the appropriate time of supplementation.

RESULTS

Forty percent (95% CI 35.1-45.0) of women had heard about FAS, 16.3% (95% CI 12.8-20.2) knew that folate affects fetal health and 5.0% (95% CI 3.1-7.6) knew that it should be taken pre-pregnancy. Level of education was strongly associated with awareness (multivariate Odds Ratio for lowest vs. highest level of education: 0.29, 95% CI 0.15-0.56).

CONCLUSIONS

Knowledge of FAS is very low among women of childbearing age in Kathmandu. Inclusion of FAS information in health awareness programs is recommended.

摘要

目的

母体叶酸缺乏与神经管缺陷（NTDs）有关，这是尼泊尔加德满都妇产医院最常见的先天性出生缺陷。围孕期补充叶酸（FAS）可以预防 NTDs。本研究旨在评估加德满都育龄妇女对 FAS 的认识。

方法

2011 年 5 月至 7 月，采用半结构式问卷对 400 名在加德满都模式医院就诊的年龄在 15 至 45 岁之间的随机患者进行调查，以了解她们对 FAS 的任何认知，了解其对胎儿发育的影响以及了解适当的补充时间。

结果

40%（95%CI 35.1-45.0）的女性听说过 FAS，16.3%（95%CI 12.8-20.2）知道叶酸会影响胎儿健康，5.0%（95%CI 3.1-7.6）知道应该在怀孕前服用。教育程度与认知水平密切相关（最低教育程度与最高教育程度的多变量优势比：0.29，95%CI 0.15-0.56）。