满足加拿大确诊早期先天梅毒监测标准的婴儿中梅毒螺旋体试验血清学转化。
Seroreversion of treponemal tests in infants meeting canadian surveillance criteria for confirmed early congenital syphilis.
机构信息
Alberta Health Services-Edmonton STI Clinic, Edmonton, Alberta, Canada.
出版信息
Pediatr Infect Dis J. 2013 Mar;32(3):199-202. doi: 10.1097/INF.0b013e318273599c.
BACKGROUND
Few data exist on the serologic outcome of treponemal tests in congenital syphilis.
METHODS
A chart review was conducted on all confirmed early congenital syphilis cases in Edmonton, Canada, from 2005-2010.
RESULTS
Of the 16 cases identified, 11 (69%) infants seroreverted their treponemal tests by 18 months. Cases that did not serorevert their treponemal tests were statistically more likely to have delayed treatment and to have higher maternal rapid plasma reagin titers at birth.
CONCLUSIONS
Our data suggest that the majority of early congenital syphilis cases will serorevert their treponemal tests by 18 months.
背景
先天性梅毒的梅毒螺旋体试验血清学结果数据有限。
方法
对加拿大埃德蒙顿 2005-2010 年确诊的所有早期先天性梅毒病例进行了图表回顾。
结果
在确定的 16 例病例中，11 例（69%）婴儿在 18 个月时梅毒螺旋体试验血清学转阴。未血清学转阴的病例在统计学上更有可能延迟治疗，并且出生时母体快速血浆反应素滴度更高。
结论
我们的数据表明，大多数早期先天性梅毒病例将在 18 个月时梅毒螺旋体试验血清学转阴。
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