Razavi D, Delvaux N, Farvacques C, Robaye E
Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Belgium.
Br J Psychiatry. 1990 Jan;156:79-83. doi: 10.1192/bjp.156.1.79.
The Hospital Anxiety and Depression Scale (HADS), a four-point, 14-item questionnaire, was tested as a screening method for adjustment disorders and major depressive disorders in a sample of 210 cancer in-patients. A receiver operating characteristic (ROC) analysis was performed, giving the relationship between the true positive rate (sensitivity) and the false positive rate (1-specificity). This makes it possible to choose an optimal cut-off point that takes into account the costs and benefits of treatment of psychological distress. For screening for major depressive disorders only, a cut-off score of 19 gave 70% sensitivity and 75% specificity. For screening for adjustment disorders and major depressive disorders taken together, a cut-off score of 13 gave 75% sensitivity and 75% specificity. HADS appears in this study to be a simple, sensitive and specific tool for screening for psychiatric disorders in an oncology in-patient population.
医院焦虑抑郁量表（HADS）是一份有14个条目的四分制问卷，在210名癌症住院患者样本中作为适应障碍和重度抑郁症的筛查方法进行了测试。进行了受试者工作特征（ROC）分析，得出真阳性率（敏感性）和假阳性率（1-特异性）之间的关系。这使得能够选择一个考虑到心理困扰治疗成本和效益的最佳临界点。仅用于筛查重度抑郁症时，临界值为19时敏感性为70%，特异性为75%。用于同时筛查适应障碍和重度抑郁症时，临界值为13时敏感性为75%，特异性为75%。在本研究中，HADS似乎是一种用于筛查肿瘤住院患者精神障碍的简单、敏感且特异的工具。
