Razavi D, Delvaux N, Bredart A, Paesmans M, Debusscher L, Bron D, Stryckmans P
Service de Médecine, Université Libre de Bruxelles, Belgium.
Eur J Cancer. 1992;28A(11):1869-72. doi: 10.1016/0959-8049(92)90025-w.
The Hospital Anxiety and Depression Scale (HADS), a four-point, 14-item self-assessment questionnaire, was tested as a screening method for psychiatric disorders in a sample of 117 Hodgkin's lymphoma and non-Hodgkin lymphoma consecutive out-patients. A receiver operating characteristic (ROC) analysis was performed, giving the relationship between the true positive rate (sensitivity) and the false positive rate (1--specificity). This makes it possible to choose an optimal cut-off score that takes into account the costs and benefits of treatment of psychiatric disorders (mainly adjustment, depressive and anxiety disorders) in a lymphoma out-patient population. A cut-off point of 10 gave 84% sensitivity and 66% specificity. HADS appears in this study to be a well accepted, simple, sensitive and specific tool.
医院焦虑抑郁量表（HADS）是一份14项的四点自评问卷，在117例霍奇金淋巴瘤和非霍奇金淋巴瘤门诊连续患者样本中作为精神障碍筛查方法进行了测试。进行了受试者工作特征（ROC）分析，得出真阳性率（敏感性）和假阳性率（1 - 特异性）之间的关系。这使得能够选择一个最佳截断分数，该分数考虑了淋巴瘤门诊患者中精神障碍（主要是适应障碍、抑郁和焦虑障碍）治疗的成本和收益。截断点为10时，敏感性为84%，特异性为66%。在本研究中，HADS似乎是一种易于接受、简单、敏感且特异的工具。
