Varoni E, Tarce M, Lodi G, Carrassi A
Department of Mining andMaterial Engineering, McGill University of Montreal, Montreal, Canada.
Minerva Stomatol. 2012 Sep;61(9):399-419.
Chlorhexidine (CHX) is one of the most commonly prescribed antiseptic agents in the dental field. It has a long-lasting antibacterial activity with a broad-spectrum of action and it has been shown to reduce plaque, gingival inflammation and bleeding. Its use is considered a powerful adjuvant to mechanical oral hygiene (brushing and flossing), especially in those cases in which it cannot be performed correctly. Available as mouthwash, gel, aerosol, spray and disks, CHX is considered a safe compound, with minimal and transitory local and systemic side effects. Data support its periodic use as an adjuvant to normal brushing and flossing in subjects unable to maintain proper oral hygiene due to physical and/or mental impairment, or lack of motivation, or decreased salivary rate. CHX is also a useful alternative to mechanical oral hygiene procedures in those cases in which they are contraindicated, e.g. after a surgical procedure, or as a preoperative rinse before procedures in which use of a dental dam is not possible. The aim of this article is to offer a complete review of literature regarding the characteristics, the applications and the problems associated with the use of chlorhexidine in the dental field.
洗必泰（CHX）是牙科领域最常用的抗菌剂之一。它具有持久的抗菌活性，抗菌谱广，已被证明可减少牙菌斑、牙龈炎症和出血。其使用被认为是机械口腔卫生（刷牙和使用牙线）的有力辅助手段，尤其是在无法正确进行机械口腔卫生的情况下。CHX有漱口水、凝胶、气雾剂、喷雾剂和药盘等剂型，被认为是一种安全的化合物，局部和全身副作用极小且短暂。数据支持在因身体和/或精神障碍、缺乏动力或唾液分泌率降低而无法保持适当口腔卫生的人群中，定期使用CHX作为正常刷牙和使用牙线的辅助手段。在机械口腔卫生程序禁忌的情况下，例如手术后，或在无法使用牙垫的手术前作为术前冲洗液时，CHX也是一种有用的替代方法。本文的目的是全面回顾关于洗必泰在牙科领域的特性、应用及使用相关问题的文献。
