Vera-Sirera Beatriz, Vera-Sempere Francisco
Department of Stomatology, School of Medicine and Dentistry, Valencia University, Valencia, Spain.
J Craniofac Surg. 2012 Sep;23(5):e412-5. doi: 10.1097/SCS.0b013e31825dace7.
Adult rhabdomyoma (AR) is an extremely uncommon benign neoplasm with mature skeletal muscle differentiation comprising approximately 2% of muscle tumors, usually affecting the soft tissue of the head and neck. Although histology of AR is characteristic, several differential diagnoses (granular cell tumor, hibernoma, oncocytoma) should be considered, and one needs to be familiar with this rare entity to exclude other neoplastic diseases. We present a case of AR, in a 54-year-old man, affecting the floor of the mouth, and call attention to the oncocytic appearance (including antimitochondrial and peroxiredoxin I immunoreactivity) of this case and its differential diagnosis analyzed at the optical, immunohistochemical, and ultrastructural level, showing the morphological and immunohistochemical features that can be confused with a salivary oncocytoma.
成人横纹肌瘤（AR）是一种极其罕见的良性肿瘤，具有成熟的骨骼肌分化，约占肌肉肿瘤的2%，通常累及头颈部软组织。尽管AR的组织学特征明显，但仍应考虑几种鉴别诊断（颗粒细胞瘤、冬眠瘤、嗜酸性细胞瘤），并且需要熟悉这种罕见实体以排除其他肿瘤性疾病。我们报告一例54岁男性的AR病例，病变位于口底，并提请注意该病例的嗜酸性外观（包括抗线粒体和过氧化物酶I免疫反应性）以及在光学、免疫组织化学和超微结构水平上进行的鉴别诊断，展示了可能与涎腺嗜酸性细胞瘤混淆的形态学和免疫组织化学特征。
