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经口内镜下肌切开术(POEM)步骤:IRCAD 引入的一项新技术

STEPS to POEM: introduction of a new technique at the IRCAD.

作者信息

Perretta Silvana, Dallemagne Bernard, Marescaux Jacques

机构信息

IRCAD Department of Digestive and Endocrine Surgery, University of Strasbourg, Strasbourg, France.

出版信息

Surg Innov. 2012 Sep;19(3):216-20. doi: 10.1177/1553350612458857.

Abstract

The future of natural orifice transluminal endoscopic surgery lies not just in the reduction of the invasiness of selected surgical procedures, but more in the development of innovative surgical concepts and revisitation of old surgical dogmas. This is particularly true for minimally invasive oesophageal surgery which is still relatively new and therefore an ideal field for improvement as it presents many unanswered questions. Endoluminal and transluminal esophageal endoscopic procedures for both diagnostic and therapeutic purposes have recently been explored. Most impressively perhaps Haruhiro Inoue{H. Inoue, 2010 #191}, has recently reported the first clinical experience of submucosal endoscopic esophageal myotomy for esophageal achalasia with a peroral endoscopic myotomy (POEM). In addition to being a no-scar technique the true innovation and appeal of the POEM procedure is that it specifically targets the circular muscle layers of the LES affected by achalasia, thereby preserving the anatomic integrity of the LES anatomy and possibly minimizing surgical side effects such as gastroesophageal reflux. However, the low incidence of in combination with POEM technical demands makes the design of a pathway to introduce this into clinical practice a challenge. We describe our recommendations for starting a POEM program based on our own experience and describe the first clinical case of POEM performed at the University of Strasbourg, as well as being the first in France, to illusa model for other institutions wishing to introduce POEM into their clinical repertory.

摘要

自然腔道内镜手术的未来不仅在于减少特定手术的侵入性,更在于创新手术概念的发展以及对旧有手术教条的重新审视。这对于微创食管手术尤为如此,因为该领域相对较新,仍存在许多未解决的问题,因此是一个理想的改进领域。最近,人们对用于诊断和治疗目的的腔内和经腔食管内镜手术进行了探索。也许最令人印象深刻的是,Haruhiro Inoue{H. Inoue, 2010 #191}最近报告了经口内镜下肌切开术(POEM)治疗贲门失弛缓症的黏膜下内镜食管肌切开术的首例临床经验。除了是一种无疤痕技术外,POEM手术的真正创新和吸引力在于它专门针对受贲门失弛缓症影响的LES环形肌层,从而保留LES解剖结构的完整性,并可能将诸如胃食管反流等手术副作用降至最低。然而,POEM技术需求与低发生率相结合,使得将其引入临床实践的途径设计成为一项挑战。我们根据自己的经验描述开展POEM项目的建议,并描述在斯特拉斯堡大学进行的首例POEM临床病例,这也是法国的首例,为其他希望将POEM纳入其临床术式的机构提供一个范例。

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