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内镜与传统甲状腺切除术治疗良性甲状腺肿瘤:一项4年经验的回顾性研究。

Endoscopic vs. conventional thyroidectomy for the treatment of benign thyroid tumors: A retrospective study of a 4-year experience.

作者信息

Cao Feilin, Xie Bojian, Cui Binbin, Xu Dong

机构信息

Department of Surgical Oncology, Taizhou Hospital, Wenzhou Medical College, Taizhou, Zhejiang 317000, P.R. China.

出版信息

Exp Ther Med. 2011 Jul;2(4):661-666. doi: 10.3892/etm.2011.267. Epub 2011 May 12.

Abstract

Endoscopic thyroidectomy (ET) allows surgeons to remove a thyroid tumor from a remote site, while providing excellent results from a cosmetic viewpoint. The aim of this study was to explore the appropriateness and outcomes of ET via breast approach for the treatment of benign thyroid tumors. A total of 637 patients with benign thyroid tumors were recruited in our department. Two hundred and eighty-five patients underwent the ET via breast approach (ET group) and 352 matched control patients underwent conventional thyroidectomy (ConT group). Variables, such as surgery-related outcomes and postoperative complications, were compared between these two groups. A unilateral lobectomy was performed in 126 patients (44.2%) of the ET group and in 163 patients (46.3%) of the ConT group. A bilateral total thyroidectomy was performed in 159 patients (55.8%) of the ET group and in 189 patients (53.7%) of the ConT group. The operative time in the ET group was longer compared to the ConT group (79.9±20.10 vs. 45.4±11.90 min, P<0.001, for unilateral lobectomy; and 89.9±14.60 vs. 60.0±8.44 min, P<0.001, for bilateral total thyroidectomy). The ET group had a significantly longer mean hospital stay compared to the ConT group (5.5±0.50 vs. 5.3±0.75 days, P=0.002). There was no case of conversion to conventional open surgery in the ET group. The recurrent laryngeal nerves and parathyroid glands were identified and protected in all cases. Our results indicate that ET performed via breast is a technically feasible and safe procedure with excellent cosmetic results for patients with benign thyroid tumors.

摘要

内镜甲状腺切除术(ET)使外科医生能够从远处部位切除甲状腺肿瘤,同时从美容角度来看能取得优异效果。本研究的目的是探讨经乳晕入路ET治疗良性甲状腺肿瘤的适用性和疗效。我们科室共招募了637例良性甲状腺肿瘤患者。285例患者接受经乳晕入路ET(ET组),352例匹配的对照患者接受传统甲状腺切除术(ConT组)。比较了两组间手术相关结局和术后并发症等变量。ET组126例患者(44.2%)行单侧甲状腺叶切除术,ConT组163例患者(46.3%)行单侧甲状腺叶切除术。ET组159例患者(55.8%)行双侧甲状腺全切除术,ConT组189例患者(53.7%)行双侧甲状腺全切除术。ET组单侧甲状腺叶切除术的手术时间比ConT组长(79.9±20.10 vs. 45.4±11.90分钟,P<0.001);双侧甲状腺全切除术的手术时间也比ConT组长(89.9±14.60 vs. 60.0±8.44分钟,P<0.001)。ET组的平均住院时间显著长于ConT组(5.5±0.50 vs. 5.3±0.75天,P=0.002)。ET组无1例转为传统开放手术。所有病例均识别并保护了喉返神经和甲状旁腺。我们的结果表明,经乳晕入路的ET对良性甲状腺肿瘤患者而言是一种技术上可行且安全的手术,美容效果良好。

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