Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
J Occup Med Toxicol. 2012 Sep 14;7(1):17. doi: 10.1186/1745-6673-7-17.
Oxalic acid poisoning is being recognized as an emerging epidemic in the rural communities of Sri Lanka as it is a component of locally produced household laundry detergents. Herein we describe a case of a 32 year old female, presenting after direct ingestion of oxalic acid. She then went on to develop significant metabolic acidosis and acute renal failure, requiring dialysis. Renal biopsy revealed acute tubulointerstitial nephritis associated with diffuse moderate acute tubular damage with refractile crystals in some of the tubules. The patient symptomatically improved with haemodialysis and renal functions subsequently returned to normal.
草酸中毒作为斯里兰卡农村社区的一种新兴流行疾病正逐渐被人们所认识,因为草酸是当地生产的家用洗衣剂的成分之一。在此,我们描述了一位 32 岁女性的病例,她因直接摄入草酸而就诊。随后,她出现严重的代谢性酸中毒和急性肾衰竭,需要进行透析治疗。肾活检显示急性肾小管间质性肾炎,伴有弥漫性中度急性肾小管损伤,部分肾小管内有折光性晶体。该患者经血液透析治疗后症状改善,肾功能随后恢复正常。