Duddy M J, Manns R A, Wormald S A
Department of Radiology, Queen Elizabeth Hospital, Edgbaston, Birmingham.
Clin Radiol. 1990 Jan;41(1):42-3. doi: 10.1016/s0009-9260(05)80931-6.
A prospective study comparing the frequency of contrast reactions by the rate of contrast injection is presented. One hundred patients undergoing excretion urography with meglumine diatriazoate (18%) and sodium diatriazoate (40%) mixture (Urografin 325) were randomised into slow (mean 0.975 ml/s) and rapid (mean 2.575 ml/s) injection groups. In the slow injection group 6 (12%) patients experienced a significant reaction as compared with 4 (8%) in the rapid injection group. There was no significant relationship between injection rate and contrast reaction (P greater than 0.1).
本文呈现了一项前瞻性研究，该研究根据造影剂注射速率比较造影剂反应的发生率。100例接受用泛影葡胺（18%）和泛影钠（40%）混合液（优维显325）进行排泄性尿路造影的患者被随机分为缓慢注射组（平均0.975 ml/s）和快速注射组（平均2.575 ml/s）。缓慢注射组中有6例（12%）患者出现明显反应，而快速注射组中有4例（8%）。注射速率与造影剂反应之间无显著关系（P大于0.1）。
