Emory University, Atlanta, GA 30322, USA.
Med Clin North Am. 2012 Sep;96(5):955-74. doi: 10.1016/j.mcna.2012.07.005.
Renal dysfunction is a common, important comorbidity in patients with both chronic and acute heart failure (HF). Chronic kidney disease and worsening renal function (WRF) are associated with worse outcomes, but our understanding of the complex bidirectional interactions between the heart and kidney remains poor. When addressing these interactions, one must consider the impact of intrinsic renal disease resulting from medical comorbidities on HF outcomes. WRF may result from any number of important processes. Understanding the role of each of these factors and their interplay are essential in understanding how to improve outcomes in patients with renal dysfunction and HF.
肾功能障碍是慢性和急性心力衰竭（HF）患者常见且重要的合并症。慢性肾脏病和肾功能恶化（WRF）与更差的结局相关，但我们对心脏和肾脏之间复杂的双向相互作用的理解仍然很差。在处理这些相互作用时，必须考虑到由合并症引起的固有肾脏疾病对 HF 结局的影响。WRF 可能由许多重要的过程引起。了解这些因素中的每一个的作用及其相互作用对于理解如何改善肾功能障碍和 HF 患者的结局至关重要。
