Gary-Rustom L, Declercq P-L, Veresezan L, Muir J-F, Cuvelier A
Unité de soins Intensifs Respiratoires, Service de Pneumologie, UPRES EA 3830, Université de Rouen, Hôpital de Bois-Guillaume, CHU de Rouen, France.
Rev Mal Respir. 2012 Sep;29(7):898-902. doi: 10.1016/j.rmr.2012.05.009. Epub 2012 Jun 12.
Sarcoidosis is a systemic granulomatous disorder. However, when epithelioid cell granulomata are found in association with malignancy, they could correspond to a sarcoid reaction.
We report the case of a young woman with mediastinal lymphadenopathy containing non-caseating granulomata. She also had a mass in the anterior mediastinum which proved, on surgical resection, to be an intrathymic mature teratoma.
An association between a sarcoid-like reaction and testicular germ cell tumours has been described in literature. Our observation of a sarcoid reaction associated with a teratoma could be due to a hypersensitivity reaction to antigen released by the tumour.
结节病是一种全身性肉芽肿性疾病。然而，当发现上皮样细胞肉芽肿与恶性肿瘤相关时，它们可能对应于结节病反应。
我们报告了一名年轻女性的病例，该患者纵隔淋巴结肿大，伴有非干酪样肉芽肿。她的前纵隔还有一个肿块，手术切除后证实为胸腺内成熟畸胎瘤。
文献中已描述了类结节病反应与睾丸生殖细胞肿瘤之间的关联。我们观察到的与畸胎瘤相关的结节病反应可能是由于对肿瘤释放的抗原产生的超敏反应。
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