Kindzel'skiĭ L P, Usatenko V D, Gubareva A A
Eksp Onkol. 1990;12(1):61-3.
Among patients with Hodgkin's disease 30 cases of the family disease were revealed during 1972-1988. The occurrence of family pairs of patients with Hodgkin's disease suggests a heritable anomaly or inheritance of a gene predisposing for this disease. In cases of contacts with second degree relatives and children from a single family, one cannot exclude a role of environmental factors and a concurrent transfer of the infectious factor. However, cases of family Hodgkin's disease might be due to a pure coincidence.
在霍奇金病患者中,1972年至1988年期间发现了30例家族性病例。霍奇金病患者家族配对的出现提示存在遗传异常或与该疾病相关的易感基因的遗传。在与二级亲属及来自单个家庭的儿童接触的情况下,不能排除环境因素的作用以及感染因子的同时传播。然而,家族性霍奇金病病例可能纯属巧合。