兄弟姐妹中的霍奇金淋巴瘤：一例报告。

Hodgkin's disease in siblings: a case report.

作者信息

Durosinmi M A, Nwosu S O, Ogunniyi J O, Dada O, Okunlola M A

机构信息

Department of Haematology and Immunology, Obafemi Awolowo University, Ile-Ife, Nigeria.

出版信息

Afr J Med Med Sci. 1989 Sep;18(3):219-22.

PMID:2551163

Abstract

Two male siblings (ages 12 and 16 years) presenting with Hodgkin's disease are reported. They were both diagnosed as stage IVB with identical histological type--lymphocyte depleted. The presence of identical sex, shared environment and the closeness of the time of onset suggested a combination of both environmental and genetic factors in the aetiology of the disease in these siblings.

摘要

报告了两名患有霍奇金病的男性同胞（年龄分别为12岁和16岁）。他们均被诊断为IVB期，组织学类型相同——淋巴细胞消减型。相同的性别、共同的环境以及发病时间的接近，提示在这些同胞中，环境因素和遗传因素共同作用导致了该病的发生。