Program in Neurosciences and Mental Health, Hospital for Sick Children Research Institute, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8.
Exp Neurol. 2013 Jul;245:27-39. doi: 10.1016/j.expneurol.2012.08.030. Epub 2012 Sep 7.
The human sensorimotor cortex demonstrates a variety of oscillatory activity that is strongly modulated by movement and somatosensory input. Studies using scalp EEG and intracranial electrical recordings have provided much of our current knowledge regarding the frequency and temporal specificity of these sensorimotor rhythms and their relationship to various movement parameters, however with limitations in identifying the underlying neural sources, and the variety of motor behaviors that can be studied, respectively. Magnetoencephalography (MEG) recordings, combined with spatial filtering source reconstruction methods, provide an ideal non-invasive method for the localization of sensorimotor rhythms and for describing their precise time course during a variety of motor tasks. This review describes the application of MEG to the study of oscillatory activity in the human sensorimotor cortex, including advances in localization techniques and recent contributions of MEG to our understanding of the functional role of these oscillations in both adult and developmental populations.
人类感觉运动皮层表现出多种振荡活动，这些活动受到运动和躯体感觉输入的强烈调节。使用头皮 EEG 和颅内电记录的研究提供了我们目前关于这些感觉运动节律的频率和时间特异性以及它们与各种运动参数的关系的大部分知识，但是在确定潜在的神经源和可以研究的各种运动行为方面存在局限性。脑磁图（MEG）记录与空间滤波源重建方法相结合，为定位感觉运动节律以及在各种运动任务中描述它们的精确时间过程提供了一种理想的非侵入性方法。本综述描述了 MEG 在研究人类感觉运动皮层中的振荡活动中的应用，包括定位技术的进展以及 MEG 对我们理解这些振荡在成人和发育人群中的功能作用的最新贡献。
