Mitofusin 2 joins the sarcoplasmic reticulum and mitochondria at the hip to sustain cardiac energetics.
作者信息
Konstantinidis Klitos, Lederer W Jonathan, Rizzuto Rosario, Kitsis Richard N
出版信息
Circ Res. 2012 Sep 14;111(7):821-3. doi: 10.1161/CIRCRESAHA.112.277269.
Abstract
摘要
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Mitofusin 2 joins the sarcoplasmic reticulum and mitochondria at the hip to sustain cardiac energetics.线粒体融合蛋白2在关键部位连接肌浆网和线粒体，以维持心脏能量代谢。
Circ Res. 2012 Sep 14;111(7):821-3. doi: 10.1161/CIRCRESAHA.112.277269.
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2
Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.含线粒体融合蛋白 2 的线粒体-网状微区通过细胞器间的 Ca²⁺ 串扰指导快速心肌细胞能量代谢反应。
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Bax regulates primary necrosis through mitochondrial dynamics.Bax 通过线粒体动力学调节原初坏死。
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Mitochondrial fusion is essential for organelle function and cardiac homeostasis.线粒体融合对于细胞器功能和心脏内稳态至关重要。
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Ca2+ dynamics in the mitochondria - state of the art.线粒体中的 Ca2+ 动力学——最新进展。
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Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes.线粒体融合蛋白 2 维持线粒体结构，并有助于心肌细胞应激诱导的通透性转换。
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