Helvaci Mehmet R, Kaya Hasan, Gundogdu Mehmet
Medical Faculty of the Mustafa Kemal University, Serinyol, Antakya, Hatay, Turkey.
Acta Med Indones. 2012 Jul;44(3):222-7.
to understand the role and significance of WCH in definition of the metabolic syndrome.
the study was performed in the Internal Medicine Polyclinic of the Dumlupinar University between August 2005 and March 2007. We took consecutive patients at and above the age of 20 years. Their medical histories including smoking habit, DM, dyslipidemia, and already used medications were learnt, and a routine check up procedure including fasting plasma glucose (FPG), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), and an electrocardiography was performed. Comparison of proportions was used as the method of statistical analysis.
the study included 1,068 cases. Prevalences of excess weight increased from the third (28.7%) up to the seventh decades (87.0%), gradually (p<0.05 nearly in all steps), and then decreased in the eighth (78.5%, p<0.05) decade of life. The most significant increase was seen during the passage from the third to the fourth decades (28.7% versus 63.6%, p<0.001) with a similar fashion to smoking. Hyperbetalipoproteinemia, hypertriglyceridemia, dyslipidemia, impaired glucose tolerance (IGT), and WCH had a similar fashion with excess weight by increasing until the seventh decade and decreasing afterwards (p<0.05 nearly in all steps). Whereas hypertension (HT), type 2 diabetes mellitus (DM), and coronary heart disease (CHD) always increased without any decrease by decades (p<0.05 nearly in all steps), indicating their irreversible natures.
WCH may be an initial sign of the systemic atherosclerotic process that can be detected easily and prevented by a trend towards weight loss.
了解白大衣高血压（WCH）在代谢综合征定义中的作用和意义。
该研究于2005年8月至2007年3月在杜姆卢平纳尔大学内科综合门诊进行。我们选取了连续的20岁及以上患者。了解他们的病史，包括吸烟习惯、糖尿病、血脂异常以及已使用的药物，并进行常规检查程序，包括空腹血糖（FPG）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）以及心电图检查。采用比例比较作为统计分析方法。
该研究纳入了1068例病例。超重患病率从第三个十年（28.7%）逐渐上升至第七个十年（87.0%）（几乎在所有阶段p<0.05），然后在第八个十年（78.5%，p<0.05）下降。从第三个十年到第四个十年期间增加最为显著（28.7%对63.6%，p<0.001），与吸烟情况类似。高β脂蛋白血症、高甘油三酯血症、血脂异常、糖耐量受损（IGT）和白大衣高血压（WCH）与超重情况类似，在第七个十年之前增加，之后下降（几乎在所有阶段p<0.05）。而高血压（HT）、2型糖尿病（DM）和冠心病（CHD）则随十年增长一直增加且无下降趋势（几乎在所有阶段p<0.05），表明它们具有不可逆性。
白大衣高血压（WCH）可能是全身动脉粥样硬化过程的初始迹象，可通过体重减轻趋势轻松检测并预防。
