Salama Maha M, Taher Eman E, El-Bahy Mohamed M
Department of Pharmacognosy, Cairo University, Cairo, Egypt.
Rev Inst Med Trop Sao Paulo. 2012 Sep-Oct;54(5):281-6. doi: 10.1590/s0036-46652012000500008.
Steam distillation of essential oils of aerial parts of Thymus capitatus and Marrubium vulgare L. collected at North cost of Egypt yielded 0.5% and 0.2%, respectively. Results of Gas chromatography-mass spectrometry analyses of the two samples identified 96.27% and 90.19% of the total oil composition for T. capitatus and M. vulgare, respectively. The two oil samples appeared dominated by the oxygenated constituents (88.22% for T. capitatus and 57.50% for M. vulgare), composed of phenols, mainly carvacrol (32.98%) and thymol (32.82%) in essential oil of T. capitatus, and thymol (34.55%) in essential oil of M. vulgare. It was evaluated the molluscicidal activity of T. capitatus and M. vulgare essential oils on adult and eggs of Biomphalaria alexandrina as well as their mosquitocidal activity on Culex pipiens. The LC50 and LC90 of T. capitatus essential oil against adult snails was 200 and 400 ppm/3hrs, respectively, while for M. vulgare it was 50 and 100 ppm/3hrs, respectively. Moreover, M. vulgare showed LC100 ovicidal activity at 200 ppm/24 hrs while T. capitatus oil showed no ovicidal activity. It was verified mosquitocidal activity, with LC50 and LC90 of 100 and 200 ppm/12hrs respectively for larvae, and 200 and 400 ppm/12hrs respectively for pupae of C. pipiens.
对采自埃及北部沿海地区的头状百里香和药用夏至草地上部分进行水蒸气蒸馏提取精油,得率分别为0.5%和0.2%。对这两个样品进行气相色谱 - 质谱分析的结果表明,头状百里香和药用夏至草的精油成分分别占总油成分的96.27%和90.19%。这两个油样均以含氧化合物为主(头状百里香为88.22%,药用夏至草为57.50%),含氧化合物由酚类组成,头状百里香精油中主要是香芹酚(32.98%)和百里香酚(32.82%),药用夏至草精油中主要是百里香酚(34.55%)。对头状百里香和药用夏至草精油对埃及双脐螺成虫和卵的杀螺活性以及对致倦库蚊的灭蚊活性进行了评估。头状百里香精油对成年蜗牛的LC50和LC90分别为200和400 ppm/3小时,而药用夏至草精油对成年蜗牛的LC50和LC90分别为50和100 ppm/3小时。此外,药用夏至草在200 ppm/24小时时表现出100%杀卵活性,而头状百里香精油则没有杀卵活性。对灭蚊活性进行了验证,对头状百里香和药用夏至草精油,致倦库蚊幼虫的LC50和LC90分别为100和200 ppm/12小时,蛹的LC50和LC90分别为200和400 ppm/12小时。