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[创伤性胎盘早剥伴弥散性血管内凝血]

[Traumatic abruption of the placenta with disseminated intravascular coagulation].

作者信息

Benz R, Malär A-U, Benz-Wörner J, Scherer M, Hodel M, Gähler A, Haberthür C, Konrad C

机构信息

Klinik für Anästhesie, chirurgische Intensivmedizin, Rettungsmedizin und Schmerztherapie, Luzerner Kantonsspital, 6000, Luzern 16, Schweiz.

出版信息

Anaesthesist. 2012 Oct;61(10):901-5. doi: 10.1007/s00101-012-2084-3. Epub 2012 Sep 16.

DOI:10.1007/s00101-012-2084-3
PMID:22983449
Abstract

Trauma in pregnancy is infrequent and a systematic primary strategy constitutes a real challenge for the interdisciplinary team. With a high fetal mortality rate and a substantial maternal mortality rate traumatic placental abruption is a severe emergency which every anesthetist should be aware of. After hemodynamic stabilization of the mother and control of the viability of the fetus the therapy of traumatic placental abruption consists mostly of an immediate caesarean section. Coagulopathy by depletion of coagulation factors as well as disseminated intravascular coagulation (DIC) have to be expected and consequently a massive blood loss must be anticipated. Thrombelastography provides assistance for fast differential diagnosis and goal-directed treatment of the disturbed sections of the coagulation cascade.

摘要

妊娠期创伤并不常见,制定系统的初级治疗策略对跨学科团队来说是一项真正的挑战。创伤性胎盘早剥是一种严重的紧急情况,胎儿死亡率高,孕产妇死亡率也很高,每位麻醉医生都应有所了解。在母亲血流动力学稳定且胎儿存活情况得到控制后,创伤性胎盘早剥的治疗主要是立即进行剖宫产。必须预计到因凝血因子消耗导致的凝血病以及弥散性血管内凝血(DIC),因此必须预见到大量失血。血栓弹力图可为凝血级联反应受干扰部分的快速鉴别诊断和目标导向治疗提供帮助。

相似文献

1
[Traumatic abruption of the placenta with disseminated intravascular coagulation].[创伤性胎盘早剥伴弥散性血管内凝血]
Anaesthesist. 2012 Oct;61(10):901-5. doi: 10.1007/s00101-012-2084-3. Epub 2012 Sep 16.
2
Abruptio placentae and disseminated intravascular coagulopathy.胎盘早剥与弥散性血管内凝血
Semin Perinatol. 2009 Jun;33(3):189-95. doi: 10.1053/j.semperi.2009.02.005.
3
Abruptio placentae with coagulopathy: a rational basis for management.胎盘早剥伴凝血功能障碍:处理的合理依据
Clin Obstet Gynecol. 1985 Mar;28(1):15-23. doi: 10.1097/00003081-198528010-00003.
4
Acute promyelocytic leukemia: an unusual cause showing prolonged disseminated intravascular coagulation after placental abruption.急性早幼粒细胞白血病:胎盘早剥后出现长时间弥散性血管内凝血的罕见病因。
Arch Gynecol Obstet. 2008 Mar;277(3):267-70. doi: 10.1007/s00404-007-0444-z. Epub 2007 Aug 23.
5
Use of uterine artery embolization to prevent peripartum hemorrhage of placental abruption with fetal demise & severe DIC.使用子宫动脉栓塞术预防胎盘早剥伴胎儿死亡及严重弥散性血管内凝血的围产期出血。
J Neonatal Perinatal Med. 2016 Sep 16;9(3):325-31. doi: 10.3233/NPM-16915108.
6
Treatment of pregnant patient with disseminated intravascular coagulation (DIC) due to placental abruption--a case report.胎盘早剥致弥散性血管内凝血(DIC)的孕妇治疗——病例报告
Clin Exp Obstet Gynecol. 2015;42(5):692-5.
7
Disseminated intravascular coagulation.弥散性血管内凝血
J Natl Med Assoc. 1985 Oct;77(10):830-2, 835.
8
The management of severe disseminated intravascular coagulopathy complicating placental abruption in the second trimester of pregnancy.妊娠中期胎盘早剥并发严重弥散性血管内凝血的处理
Br J Obstet Gynaecol. 1988 Apr;95(4):419-20. doi: 10.1111/j.1471-0528.1988.tb06618.x.
9
Disseminated intravascular coagulation in the HELLP syndrome: how much do we really know?HELLP综合征中的弥散性血管内凝血:我们究竟了解多少?
J Matern Fetal Neonatal Med. 2017 Apr;30(7):779-788. doi: 10.1080/14767058.2016.1189897. Epub 2016 Jun 8.
10
Guidelines for the Management of a Pregnant Trauma Patient.妊娠创伤患者管理指南
J Obstet Gynaecol Can. 2015 Jun;37(6):553-74. doi: 10.1016/s1701-2163(15)30232-2.

本文引用的文献

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Clinical review: Prothrombin complex concentrates--evaluation of safety and thrombogenicity.临床综述:凝血酶原复合物浓缩物——安全性和血栓形成性评估。
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Expressiveness of global coagulation parameters in dilutional coagulopathy.在稀释性凝血功能障碍中,全局凝血参数的表达。
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A novel thromboelastographic score to identify overt disseminated intravascular coagulation resulting in a hypocoagulable state.
一种新型血栓弹力描记评分系统,用于识别导致低凝状态的显性弥散性血管内凝血。
Am J Clin Pathol. 2010 Jul;134(1):97-102. doi: 10.1309/AJCPPZ4J6CAFYDVM.
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In vitro factor XIII supplementation increases clot firmness in Rotation Thromboelastometry (ROTEM).体外补充因子 XIII 可增加旋转血栓弹性描记术(ROTEM)中的血凝块硬度。
Thromb Haemost. 2010 Aug;104(2):385-91. doi: 10.1160/TH09-12-0858. Epub 2010 Apr 29.
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Trauma in pregnancy.妊娠期创伤
Clin Obstet Gynecol. 2009 Dec;52(4):611-29. doi: 10.1097/GRF.0b013e3181c11edf.
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Trauma in pregnancy.妊娠期创伤
Obstet Gynecol. 2009 Jul;114(1):147-160. doi: 10.1097/AOG.0b013e3181ab6014.
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Abruptio placentae and disseminated intravascular coagulopathy.胎盘早剥与弥散性血管内凝血
Semin Perinatol. 2009 Jun;33(3):189-95. doi: 10.1053/j.semperi.2009.02.005.
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The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage.纤维蛋白原降低是产后出血严重程度的早期预测指标。
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