Department of Radiology, GATA Haydarpasa Teaching Hospital, Uskudar, Istanbul, Turkey.
Wien Klin Wochenschr. 2012 Oct;124(19-20):704-8. doi: 10.1007/s00508-012-0233-y. Epub 2012 Sep 17.
The purpose of this study is to determine the effectiveness of the diffusion-weighted magnetic resonance imaging (DWI) of the differentiation of benign and malignant testicular masses.
Fifteen male patients who admitted to our clinic with the diagnosis of testicular mass detected by ultrasound were enrolled to this study. The patients were between 20 and 61 years old (mean 25.7). Apparent diffusion coefficient (ADC) values were measured from ADC maps of lesion and normal testicular tissue. In addition, mean signal intensity (SI) measurements were obtained by using b: 1,000 of normal testicular tissue and lesion with three regions of interest (ROI). SI ratio values are obtained by dividing the value lesion SI to the normal testicular parenchyma SI. Histopathology of orchiectomy materials and ADC values and lesion SI rates were compared statistically.
There were no significant correlation (p = 0.97) between ADC values of benign and malign lesions and histopathological diagnosis in Student's t test. There were statistically significant relationship with the histopathology of the lesion and the SI ratio in Student's t test (p = 0.027).
DWI is an effective method in differentiation of benign and malignant testicular masses. Important information can be obtained about nature of testis masses with quantitative measurements of the ADC and ratio of SI.
本研究旨在确定磁共振扩散加权成像（DWI）在鉴别睾丸良恶性肿块中的有效性。
本研究纳入了 15 名经超声检查诊断为睾丸肿块的男性患者。患者年龄在 20 岁至 61 岁之间（平均年龄 25.7 岁）。从病变和正常睾丸组织的 ADC 图上测量表观扩散系数（ADC）值。此外，通过使用 b：1000 的正常睾丸组织和病变的三个感兴趣区（ROI），获得平均信号强度（SI）测量值。通过将病变 SI 值除以正常睾丸实质 SI 值来获得 SI 比值。对睾丸切除术标本的组织病理学和 ADC 值及病变 SI 率进行统计学比较。
在学生 t 检验中，ADC 值与良性和恶性病变的组织病理学诊断之间无显著相关性（p=0.97）。在学生 t 检验中，病变的组织病理学与 SI 比值之间存在统计学显著关系（p=0.027）。
DWI 是鉴别睾丸良恶性肿块的有效方法。通过 ADC 和 SI 比值的定量测量，可以获得有关睾丸肿块性质的重要信息。
