Department of Radiology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey.
Wien Klin Wochenschr. 2011 Nov;123(21-22):655-61. doi: 10.1007/s00508-011-0053-5. Epub 2011 Sep 18.
Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions.
41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results.
Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 x 10(-3) mm(2)/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%.
DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.
本研究旨在探讨弥散加权磁共振成像（DWI）能否用于鉴别乳腺良、恶性病变。
本研究共纳入 41 例女性患者。45 个病灶经活检证实；其中 25 个（55.5%）为恶性，20 个（44.5%）为良性。前瞻性比较这些病灶的表观弥散系数（ADC）值与其组织病理学结果。
鉴别良、恶性肿块的结果显示，ADC 值的阈值为 1.0 x 10(-3) mm(2)/s，其敏感度为 95%，特异度为 100%，阳性预测值为 100%，阴性预测值为 94%，准确率为 97%。
DWI 提高了常规乳腺 MRI 的诊断准确性。ADC 值测量有助于鉴别乳腺良、恶性肿块。
