从阿尔茨海默病的逆行性发生：一种针对晚期痴呆症患者的新护理策略。
From Alzheimer's disease retrogenesis: a new care strategy for patients with advanced dementia.
机构信息
Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona 37131, Italy.
出版信息
Am J Alzheimers Dis Other Demen. 2012 Nov;27(7):483-9. doi: 10.1177/1533317512459794. Epub 2012 Sep 13.
There is evidence that exercise may reduce the progressive cognitive dysfunction of Alzheimer's disease (AD). However, no previous investigation has studiethe acute effects of adapted games (AG) on patients with AD. The aim of this study was to examine the acute effects of AG on the agitated behavior (rating scale Agitated Behavior Rating Scale [ABRS]) and cognitive performance (Test for Severe Impairment [TSI]) of patients with advanced dementia. Twenty patients (83±4 yrs) participated in AG and placebo activities (PL). Agitated behavior and cognitive performance were compared before and after 30 minutes of AG and PL. In the hour after the AG, agitated behavior decreased by ∼4 ABRS points and cognitive performance increased by ∼5 TSI points. On the contrary, after PL we found no change in agitated behavior or cognitive performance. Our data indicate that AG can momentarily reduce agitated behavior and increase the cognitive performance in participants with AD.
有证据表明，运动可能会减缓阿尔茨海默病（AD）的认知功能进行性下降。然而，之前没有研究过适应性游戏（AG）对 AD 患者的急性影响。本研究旨在探讨 AG 对晚期痴呆患者激越行为（激越行为评定量表[ABRS]）和认知表现（严重损伤测试[TSI]）的急性影响。20 名患者（83±4 岁）参与了 AG 和安慰剂活动（PL）。在 AG 和 PL 后 30 分钟比较激越行为和认知表现。AG 后 1 小时内，激越行为降低约 4 个 ABRS 点，认知表现增加约 5 个 TSI 点。相反，PL 后，我们发现激越行为或认知表现没有变化。我们的数据表明，AG 可以暂时减轻 AD 患者的激越行为，提高认知表现。
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