Johnson N, Crompton A C
Department of Obstetrics and Gynecology, St. James's University Hospital, Leeds, England.
Gynecol Oncol. 1990 Feb;36(2):217-8. doi: 10.1016/0090-8258(90)90177-m.
If there are atypical cells on a cytological smear and if the squamo-columnar junction can not be visualized during a colposcopic examination, then in order to exclude an early invasive cancer in the nonvisualized area within the endocervix it is mandatory to perform a diagnostic cone biopsy. A woman with abnormal cervical cytology and an unsatisfactory colposcopic examination who refused a cone biopsy was offered Lamicel in an attempt to expose the entire transformation zone. After 4 hr the sponge was removed and colposcopy repeated. The lesion and the squamo-columnar junction was then fully visible and she was spared a cone biopsy.
如果细胞学涂片上发现非典型细胞，并且在阴道镜检查期间无法看到鳞柱交界，那么为了排除子宫颈管内未观察到区域的早期浸润癌，必须进行诊断性锥形活检。一名宫颈细胞学异常且阴道镜检查结果不理想的女性拒绝了锥形活检，于是为其使用了Lamicel海绵，试图暴露整个转化区。4小时后取出海绵并再次进行阴道镜检查。此时病变和鳞柱交界完全可见，她无需进行锥形活检。
