Gelaw Yeshigeta, Tibebu Yemariamwork
Department of Ophthalmology, Jimma University.
Ethiop J Health Sci. 2012 Mar;22(1):1-6.
Pseudoexfoliation is the most common identifiable cause of secondary glaucoma and pseudoexfoliation patients have higher rates of intraoperative and postoperative complications of cataract surgery compared to those without the condition. Hence, the objective of this study was to assess the clinical characteristics of pseudoexfoliation syndrome among cataract patients examined at Jimma University Specialized Hospital, Southwest Ethiopia.
A cross-sectional clinic based study was conducted from January-March 2009. A total of 402 subjects with cataract were examined for the presence of pseudoexfoliation material, type of cataract, intraocular pressure, glaucoma and other factors. The presence of any exfoliation material on the iris, pupil and lens capsule was examined. Data were computed using SPSS version 16.0.
Out of the 402 patients examined, 144(35.82%) of them had presenile and senile cataract with pseudoexfoliation and out of these 144 cases, 48(33%) were unilateral and 96(66.7%) were bilateral. Furthermore, 41(28.5%) cases had raised intraocular pressure, of which 2(4.9%) cases had chronic angle closure glaucoma and 39(95.1%) of the cases had open angle pseudoexfoliative glaucoma. There was also lens sublaxation in 10(6.9%) of the cases and dislocation in 6(4.2%) of the cases. The prevalence of PEX was higher (41%) in the age group of 70 years and above followed by 60-69 years (27.8%).
A significant number of patients with PEX had poor zonular integrity and high IOP and/or glaucoma. Population based studies are recommended to assess its prevalence in the general population and its association with cataract and glaucoma.
假性剥脱是继发性青光眼最常见的可识别病因，与无该病症的患者相比，假性剥脱患者白内障手术的术中及术后并发症发生率更高。因此，本研究的目的是评估埃塞俄比亚西南部吉马大学专科医院检查的白内障患者中假性剥脱综合征的临床特征。
2009年1月至3月进行了一项基于门诊的横断面研究。共对402名白内障患者进行检查，以确定是否存在假性剥脱物质、白内障类型、眼压、青光眼及其他因素。检查虹膜、瞳孔和晶状体囊膜上是否存在任何剥脱物质。数据使用SPSS 16.0版本进行计算。
在检查的402例患者中，144例（35.82%）患有伴有假性剥脱的老年性和早老年性白内障，在这144例病例中，48例（33%）为单侧，96例（66.7%）为双侧。此外，41例（28.5%）眼压升高，其中2例（4.9%）患有慢性闭角型青光眼，39例（95.1%）患有开角型假性剥脱性青光眼。10例（6.9%）病例存在晶状体半脱位，6例（4.2%）病例存在晶状体脱位。70岁及以上年龄组的假性剥脱患病率较高（41%），其次是60 - 69岁年龄组（27.8%）。
大量假性剥脱患者的悬韧带完整性差，眼压高和/或患有青光眼。建议开展基于人群的研究，以评估其在普通人群中的患病率及其与白内障和青光眼的关联。
